Sumer Undergraduate Research Program in Neuroscience of Addiction

项目总结/摘要 此更新申请寻求支持我们完善的研究教育计划在物质使用 疾病，以支持本科生追求短期的夏季研究经验，在医学 南卡罗来纳州大学。目标是培养下一代独立研究人员 他们可以逐步加强现有的治疗方法，并开发新的方法来治疗物质使用障碍。 具体目标是：1）培养这些有才华和积极进取的学生的兴趣， 成瘾研究领域的生物医学研究，提供一个论坛， 可以成为分享他们的热情和专业知识的导师; 2）利用现有的研究培训计划， MUSC补充和扩大学生的整体经验; 3）提供一个论坛，学生 不仅获得如何解决研究问题的基础知识，而且还学习前沿研究 技术，研究道德和研究数据的呈现; 4）有助于提高学生的整体 通过培养对科学本质的理解和获得社会科学技能来提高科学素养， 价值观。（5）实施一项全面的评估计划，以衡量该计划的实施程度。 实现其目标。每年，14名本科生将有机会进行 生物医学研究项目的指导下，教师导师主要是在系 神经科学学生们进行的为期十周的夏季研究项目将以正式的 科学介绍。其他活动包括重点专题系列讲座;研究伦理 关于科学素养、专业发展和 就业机会;社会职能。参与的教师构成了一个高度协作， 由实验室研究人员组成的跨学科团队。培训机会按主题组织， 四个研究领域：可卡因复吸的神经生物学基础;甲基苯丙胺的神经生物学 药物依赖;药物使用障碍中与性和性别有关的研究;以及压力和药物使用 紊乱该计划建立在并利用（1）MUSC的强大和持续的研究承诺 培训;（2）其在为有才华的本科生提供有意义的研究经验方面的良好声誉 （3）在吸引代表性不足的群体的学生方面取得的成就， 本科院校;（4）有效的项目管理。这个R25计划将教授和促进 临床和基础科学知识的整合，重点是获得基础研究技能 物质使用的神经生物学

PROJECT SUMMARY/ABSTRACT This renewal application seeks support for our well-established research education program in substance use disorders to support undergraduate students pursuing short-term summer research experiences at the Medical University of South Carolina (MUSC). The goal is to develop the next generation of independent researchers who can progressively enhance existing therapies and develop novel approaches to substance use disorders. The specific aims are to: 1) Foster interest in these talented and highly motivated students to pursue careers in biomedical research in the areas of addiction research by providing a forum where accomplished investigators can be mentors sharing their enthusiasm and expertise; 2) Leverage existing research training programs at MUSC to complement and expand the overall experience of the students; 3) Provide a forum where students not only acquire the basics of how to address research problems, but also learn cutting edge research techniques, research ethics, and presentation of research data; 4) Contribute to enhancing the students' overall science literacy by nurturing an appreciation of the nature of science and acquisition of socioscientific skills and values.; and 5) Implement a comprehensive evaluation plan that measures the degree to which the program is achieving its objectives. Each year, fourteen undergraduate students will have the opportunity to conduct biomedical research projects under the guidance of faculty mentors based primarily in the Department of Neuroscience. The ten-week summer research projects conducted by the students will culminate in a formal scientific presentation. Additional activities include a lecture series on focused topics; a research ethics component; formal and informal discussions on the meaning of scientific literacy, professional development and career opportunities; and social functions. The participating faculty constitutes a highly collaborative, interdisciplinary team of laboratory-based researchers. Training opportunities are thematically organized around four areas of research: neurobiological basis of cocaine relapse; neurobiology of methamphetamine dependence; sex and gender related research in substance use disorders; and stress and substance use disorders. The program builds upon and leverages (1) MUSC's strong and continued commitment to research training; (2) its excellent reputation in providing meaningful research experiences for talented undergraduate students; (3) its record of accomplishment of attracting students from underrepresented groups and undergraduate institutions, and (4) its effective program management. This R25 program will teach and promote the integration of clinical and basic science knowledge, with an emphasis on acquiring research skills in the basic neurobiology of substance use.