Advancing Child Health Through Cellular and Molecular Biology

项目总结/摘要 密歇根大学儿童健康研究职业发展奖（CHRCDA）计划是 旨在支持初级儿科研究人员的职业发展。CHRCDA学者参加 在细胞和分子生物学以及教学教育计划密集，指导培训计划 以确保其持续的研究发展。自1992年成立以来，密歇根州CHRCDA 为60多名儿科医生-科学家的培训做出了贡献，其中大多数已获得R级 NIH资助儿童疾病研究。 本次更新申请的目的是：1）为初级儿科医生-科学家提供机会， 研究影响密歇根州儿童健康的疾病的基本机制和发病机制; 2） 加强儿科医生-科学家的转化研究培训; 3）继续招募最多的 有前途的初级儿科医生，科学家的培训，包括那些来自不同背景。 为了实现这些目标，项目总监Martin博士和联合培训总监Hershenson博士和 Lumeng将得到1）科学咨询委员会的协助，以监督项目方向和学者 选择和评估; 2）外部咨询委员会，对计划进行独立审查; 3） 一个教育中心，负责监督学者的教学培训;以及4）一名招聘官员，协助确定 招聘少数民族候选人。 最后，由于迫切需要培训儿科医生-科学家，密歇根大学医学院 院长办公室和儿科系已同意提供额外的配套资金，以补充 并在确定需要时，通过NIH-CHRCDA向个人提供支持。

Project Summary / Abstract The University of Michigan Child Health Research Career Development Award (CHRCDA) program is designed to support the career development of junior pediatric investigators. CHRCDA scholars participate in an intensive, mentored training program in cell and molecular biology as well as a didactic educational program designed to ensure their continued research development. Since its launch in 1992, the Michigan CHRCDA has contributed to the training of over 60 pediatrician-scientists, the majority of whom have obtained R-level NIH funding for the study of childhood diseases. The Aims of this renewal application are to: 1) Provide junior pediatric physician-scientists with the opportunity to study basic mechanisms and the pathogenesis of diseases that impact children’s health in Michigan; 2) Enhance the translational research training for pediatrician-scientists; and 3) Continue to recruit the most promising junior pediatrician-scientists for training, including those from diverse backgrounds. To achieve these Aims, the Program Director, Dr. Martin and Co-Training Directors, Drs. Hershenson and Lumeng, will be assisted by 1) a Scientific Advisory Committee to oversee program direction and scholar selection and evaluation; 2) an External Advisory Board to provide an independent review of the program; 3) an Education Core to oversee scholar didactic training; and 4) a Recruitment Officer to assist in identification and recruitment of minority candidates. Finally, due to the urgent need to train pediatrician-scientists, the University of Michigan Medical School Dean’s Office and the Department of Pediatrics have agreed to provide additional matching funds to complement and extend the support to individuals received through the NIH-CHRCDA when needs are identified.