MCW NCTN Lead Academic Participating Site

项目摘要 有效的国家癌症临床试验（NCTN）必须由具有承诺和专业知识的中心领导 在临床试验过程中。威斯康星州医学院（MCW）有45年的传统， 在开发和开展临床试验方面的科学领导力所证明的这种承诺， 此外，还与NRG肿瘤学、肿瘤学临床试验联盟、ECOG-ACRIN和SWOG合作 其他国家癌症研究所（NCI）资助的试验网络的领导和实质性收益。过去 5年来，Froedtert & MCW癌症中心（FMCWCC）经历了变革性的增长，并且... 定位于发挥持续的有意义的影响力作为一个领先的学术参与网站（LAPS）。FMCWCC 拥有一个领导团队，拥有丰富的经验、良好的业绩记录和有效的基础设施， 继续在开展试验方面提供科学领导， 并指导下一代的研究人员。妇女福利协调委员会将支持使命和行动 1）在开发重要和成功的多中心试验方面发挥领导作用， 利用MCW在临床前、转化和早期阶段的专业知识， 阶段和晚期临床研究; 2）为广泛参与的NCTN试验提供稳健的收益 所有MCW癌症学科; 3）通过指导培养下一代NCTN临床科学家 项目和先进的培训方法。MCW在全国成人临床中发挥了科学的领导作用 几十年来一直在试验计划，最近在招聘和基础设施方面进行了大量投资 大力发展临床试验项目这伴随着一个明确的承诺，即通过以下方式发展NCTN的活动： (i)在我们的癌症中心基础设施中赋予NCTN领导权;（ii）让教师参与广泛的 合作团体和其他非营利试验网络的专业知识，以开发，激活和积累， （iii）集中和扩大临床研究支持活动，以进一步提高能力， 效率和权责发生制; ㈣指导下一代调查员。

PROJECT SUMMARY An effective National Cancer Clinical Trials (NCTN) must be led by centers with commitment to, and expertise in, the collaborative clinical trials process. The Medical College of Wisconsin (MCW) has a 45-year tradition of such commitment as demonstrated by scientific leadership in development and conduct of clinical trials in association with NRG Oncology, Alliance for Clinical Trials in Oncology, ECOG-ACRIN, and SWOG, in addition to leadership and substantial accrual to other National Cancer Institute (NCI)-funded trials networks. In the past 5 years, the Froedtert & MCW Cancer Center (FMCWCC) has gone through transformative growth and is well- positioned to exert sustained meaningful influence as a Lead Academic Participating Site (LAPS). FMCWCC has a leadership team has diverse experience, a proven track record, and an effective infrastructure that will continue to provide scientific leadership in the development of trials, contribute to timely accrual and completion of trials, and mentor the next generation of investigators. FMCWCC will support the mission and the operation of the NCTN by 1) providing leadership in developing important and successful multicenter trials that address critical issues in cancer diagnosis and treatment utilizing MCW expertise in pre-clinical, translational, and early phase and advanced phase clinical research; 2) providing robust accrual to NCTN trials with wide participation by all MCW cancer disciplines; 3) Developing the next generation of NCTN clinical scientists through mentoring programs and advanced methods training. MCW has played a scientific leadership role in national adult clinical trials programs for many decades and has made substantial recent investments in recruitment and infrastructure to vigorously grow its clinical trial program. This comes with an explicit commitment to grow NCTN activities by: (i) empowering the NCTN leadership in our Cancer Center infrastructure; (ii) engaging faculty with extensive expertise in both the cooperative groups and other non-profit trials networks to develop, activate and accrue to NCTN trials; (iii) centralizing and expanding clinical research support activities to further increase capacity, efficiency and accrual; and (iv) mentoring the next generation of investigators.