Chemistry-Biochemistry-Biology Interface (CBBI) Program at Notre Dame

摘要 圣母大学的化学-生物化学-生物学接口（CBBI）项目是一个 建立了NIH资助的计划，支持培训进行研究的各种科学家 在化学和生物学相关学科的接口多学科研究。CBBI的目标 该计划旨在培养在化学和生物学的界面上有效工作的博士科学家， 能够说两门或两门以上学科的语言。CBBI计划已经建立了一个优秀的培训 为我们的实习生创造良好的环境。自2007年以来，我们已培训了84名学生，其中57人已完成 平均5.14年获得博士学位（过去10年中CBBI学员获得博士学位的时间为4.98年） 19人仍在训练中在这84人中，有16人是代表性不足的少数民族，其中10人已经 获得博士学位。我们的84名学员有362篇出版物，其中159篇是第一作者出版物。这 每名受训人员发表4.3篇论文，每名受训人员发表1.9篇第一作者论文。16个统一登记机制产生了 79篇出版物，其中31篇是第一作者出版物;这意味着每个统一资源管理机制4.9篇出版物，每个统一资源管理机制1.9篇第一作者出版物。 根据URM撰写出版物。在过去14年中，我们的减员率很低，84人中只有8人 没有完成博士学位的受训人员（9.5%）。CBBI计划的主要亮点是：1）一个大型的， 多样化的高素质候选人库; 2）合作和多学科研究的良好记录 由学员和导师; 3）一个多元化的教师群体，作为研究导师，经验丰富， 富有成效的，联邦资助的; 4）在其他领域的密集，跨学科的研究实习外 导师实验室; 5）补充培训的多学科研讨会; 6）个人和小组会议 与学员; 7）CBBI年度研讨会，在化学- 生物学接口; 8）程序管理与培养学生在化学- （9）建立一个计划和机制，以不断评估和改进培训方案; 10)专业发展和职业安置; 11）优秀的研究设施;和12）强大的 体制承诺。我们建议继续培养博士科学家的技能和专业知识，以解决 挑战性的生物医学问题，无论学科。圣母大学热情地 支持这一培训计划，并将继续为CBBI计划提供慷慨的奖学金 以及在延续拨款后的额外资源，包括所有学员的研究实习费用 由NIH。

Abstract The Chemistry-Biochemistry-Biology Interface (CBBI) Program at the University of Notre Dame is an established NIH-funded program that supports the training of diverse pool of scientists who conduct multidisciplinary research at the interface of chemistry and biology-related disciplines. The goal of the CBBI Program is to produce PhD scientists who work effectively at the interface of chemistry and biology and who are able to speak the language of two or more disciplines. The CBBI Program has established an outstanding training environment for our predoctoral trainees. Since 2007 we have trained 84 students, 57 of whom have completed PhD degrees in an average of 5.14 years (time to PhD degree from CBBI trainees is 4.98 in the past 10 years) with 19 still in training. Of these 84, 16 are underrepresented minorities (URMs), 10 of whom have already received PhD degrees. Our 84 trainees have 362 publications, of which 159 are first-author publications. This represents 4.3 publications per trainee and 1.9 first-author publications per trainee. The 16 URMs have produced 79 publications, of which 31 are first-author publications; this represents 4.9 publications per URM and 1.9 first- author publications per URM. During the past 14 years, our attrition rate has been low, with only eight of 84 trainees (9.5%) who did not complete a PhD degree. The key highlights of the CBBI Program are: 1) a large and diverse pool of highly qualified candidates; 2) a strong track record of collaborative and multidisciplinary research by both trainees and mentors; 3) a diverse faculty group that serves as research mentors and are experienced, productive, and federally-funded; 4) an intensive, cross-disciplinary research internship in the other field outside the mentor’s laboratory; 5) multidisciplinary seminars that supplement training; 6) individual and group meetings with trainees; 7) the annual CBBI symposium that features both oral and poster presentations at the chemistry- biology interface; 8) program administration with an established track record of training students at the chemistry- biology interface; 9) a plan and mechanism for continuous evaluation and refinement of the training program; 10) professional development and career placement; 11) outstanding research facilities; and 12) a strong institutional commitment. We propose to continue to train PhD scientists with the skills and expertise to solve challenging biomedical problems, regardless of discipline. The University of Notre Dame enthusiastically supports this training program, and will continue to provide a generous fellowship match to the CBBI Program and additional resources, including the cost of the research internship for all trainees, upon renewal of funding by the NIH.