UAB Predoctoral Training Grant in Translational and Molecular Sciences

这是一项新的翻译和分子科学(TMS)博士前培训拨款申请 阿拉巴马大学伯明翰分校。目前，进入职场的博士毕业生太少了 足够的疾病病理生物学培训和翻译经验，以有效地翻译分子 进入临床实践。这项建议满足了这一需求，我们的目标是提供培训 为下一代博士生物医学科学家培养必要技能的环境 将翻译目标纳入他们的研究，并为他们未来的工作做好准备。我们的 最近研究生教育的经验表明，学生对翻译培训的需求越来越大 研究。对博士前学生进行有效的翻译科学培训的一个主要挑战是需要 纳入多个学科和概念，从了解疾病机制， 了解如何在学术界或行业中转换调查结果，以了解监管监督 程序和规则。我们建议一项为期两年的计划(每年招收6名学生)，学生在 他们第二年的开始。提出了一种综合课程，它涉及到教学要素(即 包括了解疾病机制、药物发现和开发、转化研究 行政)、职业和翻译研究丰富活动(包括注册证书 翻译和分子科学、学术界和行业研讨会、CTSA互动和 基于团队的练习，培养创新、创业精神和必要的技能和知识 将发现商业化)和有意义的临床/患者互动体验，后者将是 与受训者的研究兴趣有关。我们认为为学生提供翻译研究方面的培训 在学生高考的早期阶段，将发展技能，使他们能够将翻译思维融入到 他们的研究，并为他们为未来劳动力的多样化需求做好准备。为了实现这一目标，我们有 汇集了60名培训人员，拥有资金雄厚的实验室和一系列独特的专业知识和经验， 解决基本的科学问题，特别强调翻译和人类疾病。几个 UAB长期强项的疾病领域被展示出来，并将为学生提供广泛的 不同的研究学科。这项建议强调了我们以前和现在对博士前的承诺 教育和我们为学生提供学习和发展技能的环境的集体目标 需要在生物医学研究和其他与科学相关的职业中取得成功。

This is a new pre-doctoral training grant application in Translational and Molecular Sciences (TMS) at the University of Alabama at Birmingham (UAB). Currently, too few PhD graduates are entering the workforce with sufficient training in pathobiology of disease and translational experiences to effectively translate molecular advances into clinical practice. This proposal addresses this need with our goal being to provide a training environment that develops the necessary skills for the next generation of PhD biomedical scientists to incorporate translational objectives into their research and prepare them for the workforce of tomorrow. Our recent experiences in graduate education show increased demand from students for training in translational research. A major challenge in effective training in translational sciences for pre-doctoral students is the need to incorporate multiple disciplines and concepts ranging from understanding disease mechanisms, understanding of how findings may be translated in academia or industry, to understanding regulatory oversight procedures and rules. We propose a 2 year program (with 6 students per year) with students enrolling at the beginning of their second year. An integrative curriculum is proposed that involves didactic elements (that includes understanding disease mechanisms, drug discovery and development, translational research administration), career and translational research enrichment activities (including enrollment in a Certificate program in Translational and Molecular Sciences, academia and industry workshops, CTSA interactions and team based exercises that foster innovation, entrepreneurship and requisite skills and knowledge for commercializing discoveries) and meaningful clinical / patient interaction experiences, the latter of which will be linked with the trainees’ research interests. We feel that providing students with training in translational research early during a student’s matriculation will develop skills and enable them to incorporate translational thinking into their research and prepare them for the diverse requirements for the future workforce. To achieve this, we have assembled 60 training faculty with well-funded laboratories and a unique array of expertise and experience that address fundamental scientific problems with a strong emphasis on translation and human disease. Several disease areas that are perennial strengths of UAB are represented and will provide breadth for students in diverse research disciplines. This proposal underscores our previous and ongoing commitment to pre-doctoral education and our collective goal of providing an environment for students to learn and develop the skills they will require to be successful in the biomedical research and other science related occupations.