Novel Therapies to Enhance Immunity to Cancer
Novel Therapies to Enhance Immunity to Cancer
批准号:
nhmrc : GNT1122311
负责人:
Dr Conor Kearney
金额:
$31.88万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --
中文摘要
该项目将研究一类新的靶向药物,称为Smac-mimetics。这些药物被证明在促进癌细胞死亡方面非常有效。在这里,我们的目标是更好地了解Smac模拟物如何作为癌症治疗剂以及它们如何促进对癌症的免疫反应。这将使我们能够确定既能引起癌细胞死亡又能刺激免疫系统促进肿瘤清除的联合疗法。
英文摘要
This project will investigate a new class of targeted drugs called Smac-mimetics. These drugs are proving extremely effective in promoting the death of cancer cells. Here, we aim to better understand how Smac-mimetics work as a cancer therapeutic and how they promote immune responses to cancer. This will enable us to identify combination therapies that elicit both death of the cancer cell and stimulate the immune system to promote tumour clearance.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Exploring the Inflammatory Signature of the anti-cancer Smac-mimetic, Birinapant, and the contribution of this signature to Birinapant anti-Tumour activity
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批准号:nhmrc : GNT1101244
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项目类别:Project Grants
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资助金额:$19.23万
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财政年份:2016
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负责人:Dr Conor Kearney
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依托单位:
国内基金
海外基金
Autoimmune diseases therapies: variations on the microbiome in rheumatoid arthritis
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批准号:31171277
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项目类别:面上项目
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资助金额:60.0万元
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批准年份:2011
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负责人:Christine Nardini
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依托单位:
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
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批准号:31070748
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项目类别:面上项目
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资助金额:34.0万元
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批准年份:2010
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负责人:Christine Nardini
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依托单位: