Alcohol Research Training in Neurosciences

项目摘要 这是一个有竞争力的更新申请的酒精培训计划在神经科学在大学 新墨西哥州（UNM-ARTN）。该计划目前正在结束第19年的支持，并提高了 校园里的酒精研究自2003年以来，联合国特派团-阿富汗重建和培训网络赠款支助了30名受训人员，其中10人在过去5年中接受了培训。 年在过去的5年里，我们已经填补了所有的培训名额，学员已经很好地分布在 培训教师。UNM-ARTN的目标是支持年轻研究人员的培训， 他们对酒精研究的不同领域和多种技术方法有深入的了解， 这一领域的重要问题。UNM-ARTN计划提供分子生物学，生物化学， 电生理学，成像和行为方法，4博士学位。学生每年，在这一点上，93%的 前学员已获得博士学位。度培训学院在胎儿的三个领域具有优势 酒精谱系障碍研究：1.乙醇神经致畸作用的基本机制; 2. 产前酒精暴露的生物标志物;和3。改善FASD相关认知功能的治疗干预 赤字新的举措，包括受训人员概况介绍方案、扩大的联刚特派团-阿富汗重建和培训网络研究研讨会 在UNM的培训计划中加强合作将促进技能发展和成功 过渡到有竞争力的博士后奖学金和职业生涯中的生物医学研究劳动力。共 15名教员（9名男性和6名女性）来自神经科学系、药物科学系 心理学将作为核心教师。所有项目都通过R 00、R 01或P50机制供资， 富有成效;有成功的研究指导或强大的导师培训的跟踪记录;并有广泛的 在研究赠款、出版物和指导研究生方面的合作互动。 博士前学员将从UNM健康科学的生物医学科学研究生课程中抽取 中心和UNM心理学系的认知，大脑和行为计划。该计划将 继续支持4位博士。学生每年，通常为2-3年的时间。该计划将由 Drs. Brigman和Clark将确保学员在BSGP和CBB项目中都得到很好的支持， 指导委员会由培训学院的选定成员和一名学生代表组成， 内部和外部咨询委员会。我们不同的学员已经非常成功地提出了在 科学会议，并在同行评审的期刊上发表文章。到目前为止，他们已经获得了12个博士学位 研究金/少数民族补助金，还有一项待审查。我们以前的大部分学员都去了 从事生物医学研究或在研究密集型项目中进行博士后培训，我们的目标是 继续为有前途的研究生提供必要的高质量培训，使他们为将来的研究做好准备。 在酒精研究方面取得成功。

PROJECT SUMMARY This is a competitive renewal application for an Alcohol Training Program in Neurosciences at the University of New Mexico (UNM-ARTN). This program is currently ending Year 19 of support, and has increased visibility of alcohol research across campus. Since 2003, the UNM-ARTN grant has supported 30 trainees, 10 in the past 5 years. Over the past 5 years, we have filled all our training slots and trainees have been well distributed among the training faculty. The objective of the UNM-ARTN is to support the training of young researchers and provide them with in-depth knowledge of different areas of alcohol research and multiple technical approaches to tackle important questions in this field. UNM-ARTN program provides training in molecular biological, biochemical, electrophysiologic, imaging, and behavioral approaches to 4 Ph.D. students per year, and at this point, 93% of former trainees have obtained their Ph.D. degrees. The Training Faculty has strengths in three areas of fetal alcohol spectrum disorder research: 1. Basic mechanisms involved in ethanol neuro-teratogenesis; 2. Biomarkers of prenatal alcohol exposure; and 3. Therapeutic interventions to ameliorate FASD-related cognitive deficits. New initiatives including a Trainee Orientation Program, an expanded UNM-ARTN Research Seminar and increased collaboration across training program at UNM will promote skills development and successful transitions into competitive postdoctoral fellowships and careers in the biomedical research workforce. A total of 15 faculty members (9 men and 6 women) from the Departments of Neurosciences, , Pharmaceutical Sciences and Psychology will serve as Core Faculty. All are funded via R00, R01 or P50 mechanisms, are highly productive; have a track record of successful research mentoring or strong mentor training; and have extensive collaborative interactions in terms of research grants, publications, and mentoring of graduate students. Predoctoral trainees will be drawn from the Biomedical Sciences Graduate Program of the UNM Health Sciences Center and the Cognition, Brain and Behavior Program of the UNM Psychology Department. The program will continue to support 4 Ph.D. students per year, typically for a 2-3-year period. The program will be overseen by Drs. Brigman and Clark, who will ensure trainees are well supported in both the BSGP and CBB programs, a Steering Committee composed of selected members of the Training Faculty and a student representative, and Internal and External Advisory Committees. Our diverse trainees have been very successful in presenting at scientific meetings, and publishing in peer-reviewed journals. To date, they have obtained 12 predoctoral fellowships/minority supplements, and 1 more is pending review. Most of our former trainees have gone on to pursue careers in biomedical research or postdoctoral training at research-intensive programs Our goal is to continue to provide promising graduate students with the necessary high-quality training to prepare them for a successful future career in alcohol research.