The Mayo Clinic NeuroNEXT Clinical Research Site
The Mayo Clinic NeuroNEXT Clinical Research Site
批准号:
10743328
负责人:
Nathan P Staff
金额:
$46.93万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-07-15 至 2028-06-30
关键词:
AccelerationAdultApplications GrantsArizonaAwarenessCaringChildClinicClinicalClinical ResearchClinical SciencesClinical TrialsCommunitiesCommunity TrialContractsCountryDiagnosisDiseaseEducationEligibility DeterminationEnrollmentEnsureFacultyFloridaFunding MechanismsGeographyGoalsGrantInfrastructureInstitutionInstitutional Review BoardsInterventionLeadershipLife Cycle StagesMidwestern United StatesMinnesotaMissionModernizationNational Center for Advancing Translational SciencesNational Institute of Neurological Disorders and StrokeNeurologicNeurologistNeurologyNeurosciencesParticipantPatientsPopulationPopulation HeterogeneityPositioning AttributePrincipal InvestigatorProcessProtocols documentationPublishingRare DiseasesRecording of previous eventsResearchResearch PersonnelScienceSiteStructureTherapeuticTimeTrainingTraining ProgramsTranslational ResearchTranslationsUnited StatesUnited States National Institutes of HealthWorkcareer developmentclinical centerclinical infrastructureclinical research siteexperienceimprovedinnovationmembernervous system disordernext generationnovel therapeuticspediatric patientsprogramsrare conditionresearch facilityrural settingsynergismtherapeutic developmenttrial design
中文摘要
梅奥诊所每年为约130万名患者提供服务,在临床研究和临床试验方面有着卓越的历史。它在明尼苏达州罗切斯特、佛罗里达州杰克逊维尔和亚利桑那州斯科茨代尔的最先进的研究设施使美国中西部上部、东南部和西南部的临床试验得以协调。神经科拥有200多名儿童和成人神经学家,拥有一个企业范围的领导结构,支持其综合实践、研究和教育使命。梅奥临床神经科每年治疗90,000名成人和儿童患者,拥有强大的临床研究事业。院系教员拥有各种神经系统疾病的临床专业知识和临床试验经验,包括罕见和极罕见的疾病。梅奥诊所是为NeuroNEXT提供未得到满足的需求的多样化患者和拥有这些疾病专业知识的临床试验人员的理想选择。由梅奥神经学教授发起的研究人员临床试验将针对NeuroNEXT的资助机制。这项拨款申请旨在支持、扩大和创新所有梅奥诊所的神经科学临床试验活动,提供基础设施,以确保在NeuroNEXT内的强大整合,同时利用我们的机构优势。此外,这笔赠款将支持一项创新计划,以培训下一代临床试验人员,使其在不断发展的创新试验设计和现代监管科学的格局中茁壮成长。
英文摘要
Mayo Clinic, which serves ~1.3M patients annually, has a history of excellence in clinical research and clinical trials. Its state-of-the-art research facilities in Rochester, Minnesota, Jacksonville, Florida, and Scottsdale, Arizona enable coordinated clinical trials in the upper Midwest, Southeast, and Southwest United States. The Department of Neurology, which has over 200 child and adult neurologists, has an enterprise-wide leadership structure that supports its integrated practice, research, and education mission. Mayo Clinic Neurology cares for >90,000 adult and pediatric patients annually and has a robust clinical research enterprise. Departmental faculty have clinical expertise and clinical trial experience across the full spectrum of neurological diseases, including rare and ultra-rare conditions. Mayo Clinic is ideally positioned to provide NeuroNEXT the diverse patients with unmet needs and the clinical trialists with expertise in these diseases. Investigator-initiated clinical trials by Mayo neurology faculty will be directed towards NeuroNEXT funding mechanisms. This grant application aims to support, expand, and innovate neuroscience clinical trial activities at all Mayo Clinic sites by providing the infrastructure to ensure robust integration within NeuroNEXT, while leveraging our institutional strengths. Furthermore, the grant will support an innovative program to train the next generation of clinical trialists to thrive in an evolving landscape of innovative trial design and modern regulatory science.
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专著(0)
科研奖励(0)
会议论文
PHLPP inhibition and Osteoarthritis-Associated Pain
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批准号:10581073
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项目类别:
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资助金额:$20.99万
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财政年份:2023
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负责人:Nathan P Staff
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依托单位:
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批准号:10559108
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依托单位:
Assessment of Chemotherapy-Induced Peripheral Neuropathy Susceptibility Using Patient-derived iPSC Technology
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批准号:9763518
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项目类别:
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资助金额:$35.28万
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财政年份:2017
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负责人:Nathan P Staff
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依托单位:
Assessment of Chemotherapy-Induced Peripheral Neuropathy Susceptibility Using Patient-derived iPSC Technology
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批准号:9450944
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项目类别:
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资助金额:$36.37万
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财政年份:2017
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负责人:Nathan P Staff
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依托单位:
Mechanisms of Bortezomib-induced Peripheral Neuropathy
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批准号:9093719
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项目类别:
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资助金额:$14.44万
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财政年份:2012
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负责人:Nathan P Staff
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依托单位:
Mechanisms of Bortezomib-induced Peripheral Neuropathy
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批准号:8677584
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项目类别:
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资助金额:$14.44万
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财政年份:2012
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负责人:Nathan P Staff
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依托单位:
Mechanisms of Bortezomib-induced Peripheral Neuropathy
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批准号:8505004
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项目类别:
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资助金额:$14.44万
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财政年份:2012
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负责人:Nathan P Staff
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依托单位:
Mechanisms of Bortezomib-induced Peripheral Neuropathy
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批准号:8350911
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项目类别:
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资助金额:$14.44万
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财政年份:2012
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负责人:Nathan P Staff
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依托单位:
Dopaminergic modulation of CA1 intrinsic excitability
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批准号:6634372
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项目类别:
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资助金额:$5.3万
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财政年份:2002
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负责人:Nathan P Staff
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依托单位:
Dopaminergic modulation of CA1 intrinsic excitability
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批准号:6719028
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项目类别:
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资助金额:$0.9万
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财政年份:2002
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负责人:Nathan P Staff
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依托单位:
海外基金