ShEEP Request for Bruker BioSpec 3T MRI System Upgrade

在小动物体内进行纵向磁共振成像（MRI）的能力显著提高了 并积极影响了大量VA支持的基础，转化和临床前项目 目前在Jennifer Moreno进行的与退伍军人医疗保健相关的生物医学/行为研究 VA医疗中心（JMVAMC）（以前称为VA圣地亚哥医疗保健系统）。我们有布鲁克 BioSpec 3 T小动物MRI系统，集成到集中式JMVAMC/Veterans Medical中 研究基金会显微成像核心设施，但目前的配置是有限的，在其执行能力 快速扫描，包括无法进行高质量的小鼠心脏和小鼠功能性大脑MRI 实验我们是一个由18名研究人员组成的小组，他们将直接受益于升级 现有的布鲁克BioSpec 3 T MRI系统。我们的项目将受益于升级，包括 广泛的领域和研究，包括放射学，心脏病学，骨科，生物工程，神经病学， 精神病学、肺病学、内分泌学、胃肠病学、肿瘤学和外科学。升级我们的小动物 MRI成像系统到最新的最先进的系统将不仅影响基础的临床前研究， JMVAMC，但也有望通过改善患者临床护理产生强大的积极影响。 我们的3 T系统采用的成像技术很容易被纳入临床，最终支持 退伍军人医疗使命。

The capability of performing longitudinal magnetic resonance imaging (MRI) on small animals in vivo significantly and positively impacts a large number of VA-supported projects in basic, translational and preclinical biomedical/behavioral research relevant to Veteran's healthcare currently conducted at the Jennifer Moreno VA Medical Center (JMVAMC) (formerly known as the VA San Diego Healthcare System). We have a Bruker BioSpec 3T small animal MRI system which is integrated into the centralized JMVAMC/Veterans Medical Research Foundation Microimaging Core facility, but the current configuration is limited in its ability to perform rapid scans, including the inability to perform high-quality mouse cardiac and mouse functional brain MRI experiments. We are a group of 18 investigators with active VA funding who will directly benefit from upgrading the existing Bruker BioSpec 3T MRI system. Our projects which will benefit from the upgrades encompass a wide range of fields and research, including radiology, cardiology, orthopaedics, bioengineering, neurology, psychiatry, pulmonology, endocrinology, gastroenterology, oncology, and surgery. Upgrading our small animal MRI imaging system to the latest state-of-the-art system will not only impact basic pre-clinical research at JMVAMC, but is also expected to have a strong and positive effect through improvement of patient clinical care. The imaging techniques employed on our 3T system are readily incorporated to the clinic, ultimately supporting the VA healthcare mission.