Coordinating Center Administration Core

行政核心摘要 迫切需要精心设计的研究来检验环境暴露对健康的影响 对儿童的影响。为了解决这些知识差距，环境对儿童健康的影响 结果(ECHO)计划承诺利用现有的和新的儿科队列来测试新的假说 环境暴露如何影响儿科健康。杜克临床研究所(DCRI)和 北卡罗来纳大学教堂山分校(UNC)建议继续担任ECHO协调中心 中心(ECHO CC)为管理、指导和整体提供组织框架 协调ECHO计划。DCRI是唯一准备领导这一雄心勃勃的倡议的机构。作为世界上 最大的学术研究机构，DCRI管理着活跃的网络和行政协调 该中心提供资助，并已成为儿科临床研究的领导者。为了提供内部 ECHO CC的行政结构，并确保适当的沟通和财务管理 ECHO CC，DCRI将建立ECHO协调中心管理核心。具体目标 以布莱恩·史密斯博士和琳达·阿代尔博士为首的行政核心是1)提供内部行政管理 ECHO CC的结构；2)管理ECHO CC奖励和合同；以及3)增强ECHO CC的多样性 ECHO计划中的研究、劳动力和前景。拟议的行政核心 框架将包括三个团队：协调中心管理、财务管理和承包商 管理层。协调中心管理团队将支持全面领导和 联合体的行政职能；监督整体计划管理；确保有效运作 以及内部ECHO CC员工与外部项目利益相关者和合作伙伴之间的沟通； 以及质量保证和控制。财务管理团队将负责财务报告 和预算。最后，承包商管理小组将支持所有要求的合同要求 ECHO CC包括与机会和基础设施基金相关的合同以及 发展和管理拟议的按人头支付。

ADMINISTRATIVE CORE ABSTRACT Well-designed research is urgently needed to examine the impact of environmental exposures on health outcomes in children. To address these knowledge gaps, the Environmental influences on Child Health Outcomes (ECHO) Program promises to leverage extant and new pediatric cohorts to test new hypotheses of how environmental exposures impact pediatric health. The Duke Clinical Research Institute (DCRI) and the University of North Carolina at Chapel Hill (UNC) propose to continue to serve as the ECHO Coordinating Center (ECHO CC) to provide the organizational framework for the management, direction, and overall coordination of the ECHO Program. DCRI is uniquely poised to lead this ambitious initiative. As the world's largest academic research organization, DCRI manages >30 active network and administrative coordinating center grants and has emerged as a leader in pediatric clinical research. In order to provide internal administrative structure for the ECHO CC and ensure appropriate communication and financial management of the ECHO CC, the DCRI will establish the ECHO Coordinating Center Administrative Core. The specific aims of the Administrative Core, led by Drs. Brian Smith and Linda Adair, are 1) provide internal administrative structure for the ECHO CC; 2) manage the ECHO CC award and contracts; and 3) enhance the diversity of the research, workforce, and perspectives within the ECHO Program. The proposed Administrative Core framework will include three teams: Coordinating Center Management, Financial Management, and Contractor Management. The Coordinating Center Management team will support the overall leadership and administrative functions of the consortium; oversee overall program management; ensure effective operations and communications among both internal ECHO CC staff and external program stakeholders and partners; and quality assurance and control. The Financial Management team will be responsible for financial reporting and budgeting. Finally, the Contractor Management Team will support all required contractual requirements for the ECHO CC including those contracts associated with the Opportunities and Infrastructure Fund and development and management of proposed capitation payments.