Center for Research Resources

项目总结 RCMI计划的研究资源中心(CRR)活动是 我们机构的研究企业。CRR提供先进技术方面的服务、专业知识和培训 应用包括下一代测序、基因组学、高级数据分析和其他数据密集型应用 研究领域，以及负责任的研究行为。CRR提供研究基础设施，以 不同领域的项目，是汇聚科学的主要驱动力，这也是我们机构将如何继续下去 来推动科学向前发展。CRR将由具有相关专业知识的教职员工管理。技术人员将 负责日常运营。通过向所有研究人员(例如，教职员工，受训者， 和工作人员)，我们将进一步履行NIHMD的使命，开发和交付医疗保健发现，以 服务不足的人群。CRR的目标是(1)维护尖端的设备、设施和 支持RCMI临床、基础和行为项目并加快开发 其他竞争激烈的研究项目；CRR促进涉及跨学科的合作项目 由临床和基础科学家组成的研究团队以及提供培训和专业知识。(2)面向少数群体 与调查员发展核心(START)和社区合作导致的医疗保健差距 参与核心项目(CTIHD)，以开发外部资金的新项目。重点将放在多学科上 研究团队专注于预防、诊断和治疗。(3)进一步发展研究中心 资源实验室能力，以满足新出现的需求并为RCMI社区的研究人员提供服务， 其他计划和国家/地区。通过CRR提供的服务将允许获取用于赠款的初步数据 将有助于解决健康差距的应用程序和后续出版物。通过组合 具有社区参与核心和调查员发展核心的专业知识，以及领导力 和RCMI的顾问，CRR将提供定制服务、教育/培训和研究三位一体 发展。主要领域包括生物统计学/生物信息学、基础、临床和行为研究 健康差距的原因和解决办法。CRR将支持研究人员的职业发展， 特别是新的和早期的调查人员。最后，CRR将开发新的工具和技术或重新调整用途 加快少数群体健康和健康差距科学进展的现有工具和战略。CRR 操作应遵循《标准操作程序》中规定的指导方针，该指导方针将进行修订和 随着CRR的不断扩展和发展而更新。CRR及其合作伙伴之间的协同作用将 促进基础科学和翻译科学研究，促进关于健康差距的研究，并为 在我们机构发展多样化的生物医学队伍。CRR提供必要的基础设施，以 增进我们对少数群体健康差距的了解，这样做将大大增强我们的成功 在解决这些问题上。

PROJECT SUMMARY The Center for Research Resources (CRR) activity of the RCMI Program is an essential and integral part of the research enterprise at our institution. CRR offers services, expertise, and training in advanced technology applications including Next-generation Sequencing, genomics, advanced data analysis, and other data-intensive research areas, as well as the responsible conduct of research. CRR provides the research infrastructure to projects in diverse areas and is the primary driver of convergent sciences which is how our institution will continue to move science forward. CRR will be managed by faculty with relevant expertise. Technical staff will be responsible for daily operations. By offering state-of-the-art resources to all researchers (e.g., faculty, trainees, and staff), we will further the mission of NIHMD of developing and delivering health care discoveries to underserved populations. The aims of CRR are to (1) Maintain cutting-edge equipment, facilities, and technologies to support RCMI clinical, basic and behavioral projects and to expedite the development of additional highly competitive research projects; CRR fosters collaborative projects involving transdisciplinary research teams of clinical and basic scientists as well as provide training and expertise. (2) Address minority health care disparities by working with the Investigator Development Core (START) and Community Engagement Core (CTIHD) to develop new projects for extramural funding. Emphasis will be on multidisciplinary teams with research focused on prevention, diagnosis, and treatment. (3) Further develop Center for Research Resources laboratory capability to address emerging needs and to serve investigators in the RCMI community, other programs and countries. The services through CRR will allow the acquisition of preliminary data for grant applications and subsequent publications that will contribute to resolving health disparities. By combining expertise with the Community Engagement Core and Investigator Development Core, as well as the leadership and advisors of RCMI, CRR will provide the triad of customized services, education/training, and research development. Key areas include Biostatistics/Bioinformatics, Basic, Clinical, and Behavioral Research on the causes of and solutions for health disparities. CRR will support the career development of researchers, particularly new and early-stage investigators. Lastly, CRR will develop new tools and technologies or repurpose existing tools and strategies to accelerate advances in the science of minority health and health disparities. CRR operations will follow the guidelines specified in the Standard Operation Procedures that will be revised and updated as CRR continues to expand and evolve. The synergy among CRR and its collaborating partners will facilitate basic and translational science research, stimulate studies on health disparities, and contribute to the development of a diverse biomedical workforce at our institution. CRR provides the necessary infrastructure to advance our understanding of minority health disparities and in so doing will substantially enhance our success in addressing them.