Integrative Training in the Neurobiology of Addictive Behaviors

项目摘要/摘要 芝加哥大学成瘾行为神经生物学专业的综合训练 为药物滥用相关研究的博士后和博士后学员提供培训。我们的核心教员培训师 都是富有成效的研究人员，拥有成功的培训资格。他们的专业知识从分子生物学， 药物成瘾的电生理学、药理学和动物模型，对社会、行为和 人类药物使用的精神药理学方面，包括病因、治疗和药物政策。量化 强调方法和可重复性。我们的目标是为下一代科学家做好准备 用综合方法调查药物滥用的病因、预防和治疗。 我们提出了一个计划，3名博士后和4名博士后实习生。受训人员将获得 培训计划为1-3年(通常为2年)。学员在他们的“家”接受专门的强化训练 实验室，但他们也暴露在自己领域之外的全方位成瘾研究中。至 确保学员之间以及学员和培训人员之间有实质性的互动，我们 安排每两周一次的会议，包括杂志俱乐部的报告和受邀演讲者的研讨会。 授课课程范围从分子细胞神经科学到系统和行为神经科学，从 统计学到计算神经科学和生物信息学，从遗传学和流行病学到治疗和 政策。我们T32增强训练体验的另一个机制是“外部训练”计划， 我们的受训人员在实验室或脱离他们自己的环境中获得指导经验。这个 组织结构包括执行委员会作出全面的培训决定、遴选 确保学员良好流动和平衡的委员会，监督计划和审查委员会 受训人员的进展情况，以及外部咨询委员会提供专家外部咨询。 芝加哥大学提供了一个独特的环境，既有悠久的跨学科历史 合作，以及最近对神经科学研究的重大承诺。这为我们提供了丰富的知识分子 药物滥用相关研究实习生的背景。除了T32支持的学员外，我们还有 增加了准会员，以便任何对成瘾研究感兴趣的受训人员都可以参加 T32主办的活动。这使我们能够将校园内的其他实习生和教职员工聚集在一起， 提高对成瘾研究及其与其他学科的相关性的认识。它带来了新的专业知识 并极大地丰富了培训机会。我们将投入资源招聘 我们还将提供研究道德行为方面的全面培训。

PROJECT SUMMARY/ABSTRACT The Integrative Training in the Neurobiology of Addictive Behaviors Program at The University of Chicago offers training for both pre- and postdoctoral trainees in drug abuse-related research. Our core faculty trainers are productive researchers with successful training credentials. Their expertise ranges from molecular biology, electrophysiology, pharmacology and animal models of drug addiction, to the social, behavioral and psychopharmacological aspects of human drug use, including etiology, treatment and drug policy. Quantitative approaches and reproducibility are emphasized. Our goal is to prepare the next generation of scientists to investigate the etiology, prevention and treatment of drug abuse with integrative approaches. We propose a program for 3 predoctoral and 4 postdoctoral trainees. Trainees will be supported by the Training Program for 1-3 years (usually 2 years). Trainees obtain specialized intensive training in their ‘home’ laboratories, but they are also exposed to the full breadth of addictions research outside their own area. To ensure that there is substantial interaction among the trainees, and between trainees and trainers, we schedule bi-weekly meetings consisting of journal club presentations and seminars by invited speakers. Didactic courses range from molecular cellular neuroscience to systems and behavioral neuroscience, from statistics to computational neuroscience and bioinformatics, from genetics and epidemiology to treatment and policy. One other mechanism by which our T32 has enhanced training experience is the “externship” program, in which our trainees receive mentored experiences in laboratories or settings removed from their own. The organizational structure includes an Executive Committee making overall training decisions, a Selection Committee to ensure a good flow and balance of trainees, a Program and Review Committee to monitor trainees’ progress, and an External Advisory Committee to provide expert outside consultation. The University of Chicago provides a unique environment with both a long history of interdisciplinary collaboration and recently a significant commitment to neuroscience research. This provides a rich intellectual context for trainees in drug abuse related research. In addition to the trainees supported by the T32, we have added Associate Members so that any trainee who is interested in addiction research can participate in any of the T32 sponsored activities. This allows us to bring together other trainees and faculty from across campus to raise consciousness about addiction research and its relevance to other disciplines. It brings in new expertise to the group and significantly enriches training opportunities. We will devote resources to recruiting underrepresented minorities and we will provide comprehensive training in ethical conduct of research.