TESTING INSULT ACCUMULATION WITH COMPETING MODELS

这是香农奖，为这项研究提供部分支持 项目低于指定研究所的资助范围，但 都在最优秀的边缘。香农奖旨在提供 支持测试该方法的可行性；开发进一步的测试 并改进研究方法；进行二次分析或可用 数据集；或执行可演示PI的离散项目 研究能力或为已经功成名就的 申请。下面的摘要摘自原始文件 由首席调查员提交。 描述：拟议中的研究将比较两种模型的效果 据信，成年早期的健康经历会影响 后来的健康和死亡的时间。在疾病的自然历史中 模型中，人们的期望是特定的疾病可以预测随后 健康问题。在广义侮辱累积模型中， 人们的期望是，疾病和伤害通常被认为是侮辱 这会影响到后来的健康问题。将对这些型号进行比较 使用了1451名属于友好协会的男性和女性的数据 1893-1974年期间的澳大利亚。

THIS IS A SHANNON AWARD PROVIDING PARTIAL SUPPORT FOR THE RESEARCH PROJECTS THAT FALL SHORT OF THE ASSIGNED INSTITUTE'S FUNDING RANGE BUT ARE IN THE MARGIN OF EXCELLENCE. THE SHANNON AWARD IS INTENDED TO PROVIDE SUPPORT TO TEST THE FEASIBILITY OF THE APPROACH; DEVELOP FURTHER TESTS AND REFINE RESEARCH TECHNIQUES; PERFORM SECONDARY ANALYSIS OR AVAILABLE DATA SETS; OR CONDUCT DISCRETE PROJECTS THAT CAN DEMONSTRATE THE PI'S RESEARCH CAPABILITIES OR LEND ADDITIONAL WEIGHT TO AN ALREADY MERITORIOUS APPLICATION. THE ABSTRACT BELOW IS TAKEN FROM THE ORIGINAL DOCUMENT SUBMITTED BY THE PRINCIPAL INVESTIGATOR. DESCRIPTION: The proposed research will compare the effects of two models by which health experience in early adulthood is believed to influence later health and the timing of death. In the natural history of disease model, the expectation is that specific diseases predict subsequent health problems. In the generalized insult accumulation model, the expectation is that diseases and injuries in general qualify as insults that influence later health problems. These models will be compared using data on 1451 men and women who belonged to friendly societies in Australia in the period 1893-1974.