2009 Fertilization and Activation of Development Gordon Research Conference

描述(由申请者提供)：第十七届戈登研究会议(GRC)将提供一个论坛，介绍和讨论这一令人兴奋、快速发展的领域的新发展和想法。本次会议将于2009年7月12日至7月17日在新罕布夏州普利茅斯的霍尔德内斯学校举行。自1974年以来，该会议每两年举行一次。这是唯一一次戈登研究会议，涉及受精和激活受精卵开始胚胎形成过程的关键过程中雄配子和雌配子的相互作用。它为在该领域工作的生物化学家、细胞生物学家、分子生物学家、生理学家、遗传学家和生物物理学家提供了一个互动的场所。这次会议非常成功地促进了经验和资历迥异的科学家之间的合作，以及美国和欧洲、日本、澳大利亚和拉丁美洲的研究实验室之间的合作。这些合作取得了许多丰硕成果。按照戈登研究会议的形式，会议将有九场会议。它们是：1)配子分化。(2)精子成熟和获能。3)配子和胚胎生物学的新方法。(4)受精、激活发育。5)精子鞭毛的调节。6)卵和胚胎的极性。7)关键笔记讲座-配子识别蛋白的进化。8)卵膜与精子顶体反应。9)胚胎发生和表观遗传学。这些会议将包括预定的演讲者，可能还包括从海报中选择的一些简短演讲。特别重视初级科学家，包括博士后研究员和研究生。 公共卫生相关性：戈登受精和发育激活研究会议关注的是精子和卵子在受精的关键过程中的相互作用，以及受精卵开始胚胎形成过程的激活，这是人类生育能力的关键过程。它为在该领域工作的生物化学家、细胞生物学家、分子生物学家、生理学家、遗传学家和生物物理学家提供了一个互动的场所。这次会议将促进美国和国际科学家之间在解决人类不孕不育、胚胎发育激活、干细胞生物学和避孕方面的合作，这些科学家的经验/资历、方法和模型系统大相径庭。

DESCRIPTION (provided by applicant): The Seventeenth Gordon Research Conference (GRC) on Fertilization and the Activation of Development will provide a forum for presentation and discussion of new developments and ideas in this exciting, rapidly advancing field. This meeting will be held at the Holderness School, Plymouth, New Hampshire, July 12 - July 17, 2009. This conference has been held every two years since 1974. It is the only Gordon Research Conference concerned with the interaction of the male and the female gametes in the vital process of fertilization and activation of the fertilized egg to begin the process of embryo formation. It provides a venue for the interaction of biochemists, cell biologists, molecular biologists, physiologists, geneticists, and biophysicists working in the field. This conference has been singularly successful in fostering collaborations among scientists with widely disparate experience and seniority and, among research laboratories in this country and in Europe, Japan, Australia and Latin America. These collaborations have borne many fruitful results. There will be nine sessions in the conference, following the Gordon Research Conference format. They are: 1) Gamete Differentiation. 2) Sperm epididymal maturation and capacitation. 3) New approaches to gamete and embryo biology. 4) Fertilization and activation of development. 5) Sperm flagellar regulation. 6) Egg and embryo polarity. 7) Key Note Lecture - Evolution of gamete recognition proteins. 8) Egg envelopes and the sperm acrosome reaction. 9) Embryogenesis and epigenetics. These sessions will include both scheduled speakers and possibly some selected short talks chosen from posters. Particular emphasis has been placed on junior scientists, including postdoctoral fellows and graduate students. PUBLIC HEALTH RELEVANCE: The Gordon Research Conference on Fertilization and the Activation of Development is concerned with the interaction of sperm and eggs in the vital process of fertilization and activation of the fertilized egg to begin the process of embryo formation, which are key processes underlying human fertility. It provides a venue for the interaction of biochemists, cell biologists, molecular biologists, physiologists, geneticists, and biophysicists working in the field. The conference will promote collaborations to address human infertility, activation of embryonic development, stem cell biology, and contraception among US and international scientists with widely disparate experiences/seniority, methodologies, and model systems.