2009 Periodontal Disease GRC

描述（由申请人提供）：本提案为将于2009年8月2 -7日在新罕布什尔州新伦敦的科尔比-索耶学院举行的戈登牙周病研究会议提供部分支持。会议的长远目标是增进我们对牙周病发生、发展和预防的基本机制的了解。本次会议的具体目标是召集28名代表直接影响牙周病研究的关键科学领域的发言人，共有135名与会者，在一个相对孤立的环境中举行为期五天的会议。会议的一个重要特点将是由牙周病学领域以外的主要科学家以及该学科内的专家发表与这些主题相关的演讲。欢迎学术界和工业界的参与者，并强烈鼓励所有人以海报的形式展示他们最近未发表的发现。会议安排了充足的时间进行海报讨论，并将选出一些海报在会议期间进行简短的口头演讲。此外，欢迎研究生和年轻的博士后科学家申请，并预计将向选定的参与者颁发旅行奖。该计划将有八个会议，广泛讨论牙周病的当前问题，如微生物基因组学，口腔微生物的毒力特征，细菌生物膜动力学，宿主-微生物识别，先天免疫，细胞信号传导，控制炎症，表观遗传变化和宿主反应的microRNA控制，抗原呈递和特异性免疫反应，伤口愈合机制和干细胞和组织再生。这项申请的意义在于，戈登牙周病研究会议是促进研究人员、发展中的年轻科学家和其他负责科学发展的国际科学研究人员之间科学前沿发展的成长、发展和开放交流的关键机会。这一应用与健康的关系是，会议将产生和确定在影响牙周病的发病、进展、宿主易感性和治疗方式的领域需要实验解决的问题。

DESCRIPTION (provided by applicant): This proposal requests partial support for a Gordon Research Conference on Periodontal Disease to be held August 2 -7, 2009 at Colby-Sawyer College in New London, New Hampshire. The broad and long term goal of the conference is to increase our understanding of the fundamental mechanisms involved in the initiation, progression, and prevention of periodontal diseases. The specific aims of this meeting will be to convene 28 speakers that represent critical scientific fields that directly affect periodontal disease research with a total of 135 participants for a five-day conference in a relatively isolated setting. An important feature of the meeting will be presentations relevant to these topics by leading scientists from outside the field of periodontology in addition to expert contributions from within the discipline. Academic and industrial participants are welcome and all are strongly encouraged to present their most recent unpublished findings as posters. Ample time has been allotted for poster sessions and a number of posters will be selected for short oral presentations during the conference. Furthermore applications are welcomed from graduate students and young postdoctoral scientists and it is anticipated that travel awards will be awarded to selected participants. The program will have eight sessions that broadly address current issues in periodontal disease such as microbial genomics, virulence characteristics of oral microorganisms, bacterial biofilm dynamics, host-microbe recognition, innate immunity, cell signaling, controlling inflammation, epigenetic changes and microRNA control of host responses, antigen presentation and the specific immune response, mechanisms of wound healing and stem cells and tissue regeneration. The significance of this application is that the Gordon Research Conference on Periodontal Disease is a critical opportunity to promote growth, development, and open communication of frontier developments in science among investigators, young scientists in development, and other persons responsible for the growth of science in the international community of scientific researchers. The health relatedness of this application is that the Conference will generate and define the questions that require experimental resolution in areas that affect the initiation, progression, host susceptibility, and therapeutic modalities for the treatment of periodontal diseases. PUBLIC HEALTH RELEVANCE: The health relatedness of this application is that the discussions of current research will generate and define the questions that require experimental resolution in areas that affect the initiation, progression, host susceptibility, and therapeutic modalities for the treatment of periodontal diseases. These discussions will focus researchers identifying the mechanisms controlling periodontal diseases and developing therapies based on these mechanisms.