Diabetic Retinopathy Clinical Research Network Coordinating Center

描述（由申请人提供）：本申请为糖尿病视网膜病变临床研究网络（DRCR.net）协调中心申请为期五年的延期资助。DRCR.net的目标是发展和维护一个合作网络，以促进糖尿病视网膜病变、糖尿病黄斑水肿及相关疾病的多中心临床研究，这些疾病是美国和世界各地视力损害和失明的主要和日益增长的原因。其优先事项包括参与以社区为基础的实践以及以大学为基础的中心，并与工业界合作，以促进调查和机会，否则是不可能的，但要以与网络致力于学术诚信和最佳临床试验性能一致的方式这样做。协调中心在该网络实现其目标的能力方面起着关键作用。在下一个资助周期，该网络建议完成5项预计在资助期开始时正在进行的方案，启动大约10项针对糖尿病视网膜病变、糖尿病黄斑水肿及相关病症的新方案（每年大约1项新的主要方案和1项新的次要方案），开发和实施视网膜图像电子数据捕获的新方法，以促进糖尿病视网膜病变临床试验的开展。通过邀请新站点的参与和鼓励最近完成研究金培训的研究人员的参与（见运营中心提案），继续扩大DRCR.net，继续对DRCR.net研究人员进行临床研究原则的教育，并指导选定的视网膜专家在糖尿病视网膜病变和相关疾病的临床试验中担任领导。

DESCRIPTION (provided by applicant): This application is for a five-year extension of funding for the Diabetic Retinopathy Clinical Research Network (DRCR.net) Coordinating Center. The objective of the DRCR.net is to develop and maintain a collaborative network to facilitate multicenter clinical research on diabetic retinopathy, diabetic macular edema and associated conditions, leading and growing causes of vision impairment and blindness in the United States and throughout the world. Its priorities include involvement of community-based practices as well as university-based centers and to collaborate with industry to facilitate investigations and opportunities otherwise not possible, but to do so in a manner consistent with the Network's dedication to academic integrity and optimal clinical trial performance. The Coordinating Center plays a key role in the Network's ability to achieve its goals. During the next funding cycle, the network proposes to complete 5 protocols that are expected to be in progress at the time the funding period begins, initiate approximately 10 new protocols (approximately 1 new major protocol and 1 new minor protocol per year) in diabetic retinopathy, diabetic macular edema and associated conditions, develop and implement new methods for electronic data capture of retinal images to facilitate the conduct of diabetic retinopathy clinical trials, continue to expand the DRCR.net by soliciting the participation of new sites and encouraging the involvement of investigators who recently have completed fellowship training (see Operations Center proposal), continue to educate the DRCR.net investigators on the principles of clinical research, and mentor selected retina specialists to be leaders in clinical trials with specific reference to diabetic retinopathy and associated diseases.