Community to Molecular Approaches in Early Screening and Diagnosis to Promote Equitable Outcomes Through the Continuum of Care in Cancer Among Populations of African Ancestry

项目摘要 非洲-加勒比癌症联盟（AC 3）是福克斯蔡斯癌症中心的全球肿瘤学项目 并在解决涉及非洲裔美国人、加勒比海地区和非洲裔美国人的癌症差异方面发挥着独特的作用。 美国移民（U.S.）和他们在本国的同行。AC 3成员是跨- 学科（基础和人口科学研究人员，临床医生和癌症倡导者），由三个 互联网络（美国，加勒比和非洲）。我们2023年的会议主题：“从社区到分子 早期筛查和诊断方法，通过连续护理促进公平结果 在非洲癌症人群中的癌症”反映了我们成员的跨学科构成。 此外，正如我们在以前的会议上所取得的成就，我们的2023年会议组委会，发言人和 观众将充分反映我们成员的多样性。在美国和全世界，癌症杀死更多的黑人 比任何其他种族/民族群体。大量过早的癌症死亡也主要发生在黑人中。 撒哈拉以南非洲和加勒比地区的国家。对黑人的癌症研究仍然深刻 这不仅是美国所缺乏的，也是非洲和加勒比地区黑人占主导地位的国家所缺乏的。的数量 来自非洲和加勒比地区的生物医学研究出版物正在增加，但差距仍然存在， 研究文章聚焦癌症。黑人科学家在NCI资助中的代表性也严重不足 受惠人士因此，一个训练有素的黑人科学家的国际骨干增加了急需的多样性 在全球癌症研究者中。考虑到美国黑人人口的多样性， 加勒比和非洲是包容性的，对于解决美国的癌症差异也是至关重要的。 研究方法在美国将是最有益的，因为这些研究对提供信息和改进至关重要。 在所有美国黑人中进行癌症干预、治疗和预防。AC 3科学与培训 因此，这次会议是正当、及时和有益的。我们以癌症为重点的培训，科学交流和 合作规划研讨会将布恩AC 3努力加速癌症研究， 黑人科学家的职业生涯，并提供创新的机会，研究癌症的差异，影响黑人 在美国.具体目标如下：1）通过提供专业发展来增强多样性， 教育和科学培训，以加强健康差距的研究，技能和能力， 代表性不足和服务不足的早期研究人员和学生。2)促进知识交流 在非洲裔人口中开展癌症科学研究，并增加研究开发和 协调对黑人群体的研究。3)通过科学提供，促进健康公平 严格的，临床和文化上知情的研究，为更大的社区利益，以提高 知识、癌症风险意识、降低和预防癌症风险的策略。

PROJECT SUMMARY The African-Caribbean Cancer Consortium (AC3) is a Global Oncology Program at Fox Chase Cancer Center and plays a unique role by addressing cancer disparities involving African American, Caribbean and African immigrants in the United States (U.S.) and their counterparts in native countries. AC3 membership is trans- disciplinary (basic and population science researchers, clinicians, and cancer advocates) and consists of three interconnected networks (U.S., Caribbean and Africa). Our 2023 conference theme: “Community to Molecular Approaches in Early Screening and Diagnosis to Promote Equitable Outcomes Through the Continuum of Care in Cancer Among Populations of African Ancestry” reflects the trans-disciplinary makeup of our membership. Also, as we have achieved in prior conferences, our 2023 conference organizing committees, speakers and audiences will fully reflect the diversity of our membership. In the U.S. and worldwide, cancer kills more Blacks than any other racial/ethnic group. A great number of premature cancer deaths also occur in predominantly Black nations in Sub-Saharan Africa and the Caribbean. Cancer research in Black populations remains profoundly lacking not only in the US but also in Black dominant countries in Africa and the Caribbean. The number of biomedical research publications from Africa and the Caribbean are increasing, but disparities remain for research articles focused on cancer. Black scientists are also grossly underrepresented among NCI grant recipients. Therefore, an international cadre of well-trained Black scientists increases the much needed diversity among global cancer researchers. Considering the diversity of the U.S. Black population, cancer research in the Caribbean and Africa is inclusive and also essential for addressing cancer disparities in the U.S. This equitable approach to research will be most beneficial in the U.S. as these studies are critical to inform and improve interventions, treatment and prevention of cancers among all U.S. Blacks. The AC3 Scientific and Training Conference is therefore justified, timely and useful. Our cancer-focused training, scientific exchange and collaboration planning workshops will be a boon to the AC3 efforts to accelerate cancer research, advance careers of Black scientists and provides innovative opportunities to study cancer disparities that impact Blacks in the US. The following are the Specific Aims: 1) To enhance diversity by providing professional development, education and scientific training, to strengthen health disparities research, skills and competencies among underrepresented and underserved early stage investigators and students. 2) To facilitate knowledge exchange of the science of cancer among African-descent populations, and increase research development and the coordination of research studies in Black populations. 3) To promote health equity by providing scientifically rigorous, and clinically and culturally informed research for greater community benefit in order to improve knowledge, awareness of cancer risk, strategies for cancer risk reduction and prevention.