The Gastrointestinal Epithelium Conference - Interface with the Outside World

项目摘要/摘要 本申请请求部分支持FASE B名为“胃肠”的科学研究会议 《上皮：与外部世界的接口》将于2023年9月17日至21日在蒸汽船举行 科罗拉多州斯普林斯会议将召集不同的发言者群体，其中包括许多代表不足的妇女。 少数族裔和年轻的研究人员，讨论胃肠道上皮的生物学及其在 动态平衡和疾病。主旨演讲和七场讲座将讨论胃肠道问题。 干细胞在损伤/疾病中的稳态和可塑性；干细胞的发育和分化 食道、胃、小肠和结肠的损伤修复、增殖和再生； 细胞-细胞相互作用；宿主-病原体相互作用；肠道屏障；缺氧、炎症和IBD；以及癌症。 将留出充足的时间供与会者讨论，并将介绍未公布的数据 要优先考虑。还将有两个海报会议以及几个职业发展活动 职业调查员和实习生，以及提高这些人的知名度的机会 代表着这一领域的未来。我们组织了一项创新计划，并承诺参与其中 在胃肠道相关研究领域拥有不同专业知识的领导者。总体而言，在一个亲密而隐蔽的环境中 这鼓励各级科学家之间的非正式互动，我们提供了一种创新的方法来 将推动GI研究领域向前发展的思想交流和科学综合。会议将于 影响很大，因为该计划涵盖了基础科学发现，对胃肠道健康和 疾病。因此，预计这次会议将提供新的见解，不仅是对基本胃肠道 生理学、神经生物学、发育生物学和微生物学，但也包括如何治疗并最终治愈 各种各样的消化系统疾病状态。

Project summary/abstract This application requests partial support for a FASEB Scientific Research Conference entitled “Gastrointestinal Epithelium: Interface with the Outside World” that is scheduled for September 17-21, 2023 in Steamboat Springs, CO. The meeting will convene a diverse group of speakers, including many women, underrepresented minorities, and young investigators, to discuss the biology of the gastrointestinal epithelium and its role in homeostasis and disease. The keynote presentations plus seven lecture sessions will address gastrointestinal stem cell homeostasis and plasticity in response to injury/disease; development and differentiation of the epithelium; injury repair, proliferation, and regeneration in the esophagus, stomach, small intestine, and colon; cell-cell interactions; host-pathogen interactions; intestinal barrier; hypoxia, inflammation and IBD; and cancer. Ample time will be set aside for discussions amongst participants, and the presentation of unpublished data will be prioritized. There will also be two poster sessions as well as several career development activities for early career investigators and trainees, as well as opportunities to promote the visibility of these individuals who represent the future of the field. We have assembled an innovative program with committed participation from leaders with diverse expertise within GI-related research fields. Overall, in an intimate and secluded setting that encourages informal interactions between scientists at all levels, we provide an innovative approach to the exchange of ideas and synthesis of science that will move the field of GI research forward. The conference will have high impact as the program spans basic science discovery to clinical significance for GI health and disease. It is therefore expected that the meeting will provide new insights not only into basic gastrointestinal physiology, neurobiology, developmental biology and microbiology, but also how to treat, and ultimately cure, a wide variety of digestive disease states.