课题基金 / 基金详情

NEW AVIAN LUNG, RIGIDITY OF CAPILLARIES, EPITHELIAL BRIDGES, AIR CAPILLARIES

NEW AVIAN LUNG, RIGIDITY OF CAPILLARIES, EPITHELIAL BRIDGES, AIR CAPILLARIES
新禽肺、毛细血管刚性、上皮桥、空气毛细血管
批准号:
7957653
负责人:
JOHN WEST
金额:
$4.83万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-06-15 至 2010-03-31

项目摘要

项目成果

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中文摘要
翻译
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者(PI)可能从另一个NIH来源获得了主要资金, 因此可以在其他CRISP条目中表示。所列机构为 研究中心,而研究中心不一定是研究者所在的机构。 鸟类和哺乳动物这两大类能够持续高耗氧的脊椎动物在生理上有许多相似之处,但肺却截然不同。有证据表明,鸟类的肺循环与哺乳动物的肺循环非常不同,因为鸟类的肺毛细血管似乎基本上是刚性的。其原因尚不清楚,但可能必须对毛细血管周围的组织进行超微结构检查,而NCMIR的高压电子显微镜断层扫描设备非常适合阐明这个问题。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The two great classes of vertebrates capable of sustained high oxygen consumptions, the birds and mammals, share many similarities of physiology but have radically different lungs. There is evidence that the avian pulmonary circulation is very different from that in mammals in that the avian pulmonary capillaries appeared to be essentially rigid. The reason for this are not understood but probably have to do ultrastructure of the tissues surrounding the capillaries, and the facilities of the NCMIR with its high voltage electron microscope tomography are well suited to elucidating this problem.
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