Priming the Pump: Training Physician-Scientists for Translational Neuroscience

描述（由申请人提供）：该提案旨在制定和实施住院医师培训研究轨道，其明确目标是招募具有研究记录的医学博士，博士和医学毕业生。该项目将提供早期临床研究的机会，以激发基础科学学员对转化研究的兴趣。该计划提供7个月的住院和门诊临床研究环境的转化研究机会，以及16个月的受指导研究项目的保护时间。在这几个月里，将由担当“元导师”的pi监督的密集指导，以及以伦理、统计、研究设计和转化研究原则为重点的指导。所有这些都将在满足ACGME要求的同时实现，因此毕业生将有资格获得董事会的资格。我们预计，这样的轨道，我们的概念是一个4年的计划，将允许研究轨道的居民“启动”他们的研究生涯，而仍然是居民，使他们更好地准备研究奖学金和K奖过程，最终导致董事会资格，我们为我们的学员提供一个“无风险”的路径，以提高成功的可能性作为独立调查员。这种方法的目的是纠正目前的状况，即医学博士和博士经常面临着在临床培训的需要造成的中断后“重新开始”他们的研究。我们期望教育医师科学家来加强转化研究者的管道，这是NIMH的一个关键目标。

DESCRIPTION (provided by applicant): This proposal aims to develop and implement a residency training research track with the explicit goal of recruiting MD, PhD and medical graduates with a track record in conducting research. The program will provide early exposure to clinical research to stimulate interest in translational research among our basic science trainees. The program provides 7 months of exposure to translational research in both inpatient and outpatient clinical research settings, and 16 months of protected time for a mentored research project. These months will be augmented by intensive mentoring, overseen by the PIs, functioning as "meta-mentors," as well as preceptorship focused on ethics, statistics, research design and principles of translational research. All this will be attained while meeting ACGME requirements so that graduates will be board eligible. We anticipate that such a track, which we conceptualize as a 4 year program, will permit research track residents to "jump start" their research career while still residents, rendering them to better prepared for research fellowships and the K award process, ultimately leading to board eligibility, we offer our trainees a "no-risk" path towards enhanced likelihood of success as independent investigators. This approach is intended to remedy the current state of affairs wherein MD, PhDs often are faced with "re-starting" their research after a hiatus created by the need for clinical training. We anticipate educating physician-scientists to enhance the pipeline of translational investigators, a key goal of the NIMH.