Building Trust Between Minorities and Researchers

描述（由申请人提供）：在少数民族和研究人员之间建立信任少数民族在公共卫生和生物医学研究中的代表性仍然落后于白人。这是对研究结果的有效性和普遍性的持续挑战，从而导致健康状况和护理方面的差异，这两者都构成对没有代表的少数群体的不公正。影响少数群体参与的因素有很多，包括缺乏获得研究的机会、缺乏知识和不信任，以及研究人员和卫生专业人员的态度等障碍。该提案联合了一个强大的公共卫生研究人员、生物伦理学家、多个临床和转化科学研究所以及医学和研究中的公共责任组织，提出了第一个同时寻求影响少数民族社区、调查人员和IRB成员的努力。利用定性和定量方法，我们将检查研究人员的态度、知识和行为，并确定社区参与的最佳实践；确定仅在全国少数民族随机抽样中对研究的知识水平、知情同意和参与研究的意愿；为少数民族社区制定、试点测试和修订“建立信任”课程；最后，制定和实施多种培训，旨在提高研究人员和伦理委员会成员支持招聘和与少数民族社区接触的能力。我们的首要目标是创建一个可持续的培训和教育活动基础设施，可以随着时间的推移进行评估，以确定它们对提高少数民族参与研究的影响。我们“建立信任”生物伦理研究基础设施倡议的目标是制定、实施和评估旨在增加少数民族参与生物医学和公共卫生研究（包括临床试验）的战略。我们的活动将产生有效的、可持续的工具，这些工具可以被实施和评估，以确定它们在多大程度上有助于增加少数民族参与NIH赞助的研究，并提高致力于这一目标的研究人员的自我效能。

DESCRIPTION (provided by applicant): Building Trust between Minorities and Researchers The representation of minorities in public health and biomedical research still lags behind that of whites. This represents an ongoing challenge to the validity and generalizability of research findings, which consequently contributes to disparities in health status and care, both of which constitute an injustice to unrepresented minority groups. There are multiple factors that influence the participation of minorities, including that lack of access to research, lack of knowledge and distrust, and barriers such as attitudes of researchers and health professionals. This proposal unites a strong team of public health researchers, bioethicists, multiple Clinical and Translational Science Institutes, and the organization, Public Responsibility in Medicine and Research, to propose the first effort that seeks simultaneously to impact minority communities, investigators and IRB members. Utilizing qualitative and quantitative methods, we will examine the attitudes, knowledge and behaviors of researchers and identify best practices in community engagement; determine the level of knowledge about research, informed consent and willingness to participate in research among a national random sample of minorities only; develop, pilot test and revise a curriculum, "Building Trust" for minority communities; and finally, develop and implement multiple trainings aimed at enhancing the capacity of researchers and IRB members to support recruitment and engagement with minority communities. Our over- arching goal is to create a sustainable infrastructure of training and educational initiatives, which can be evaluated over time to determine their impact on improving minority participation in research. The goal of our "Building Trust" Bioethics Research Infrastructure Initiative is to develop, implement and evaluate strategies aimed at increasing minority participation in biomedical and public health research, including clinical trials. Our campaign will produce effective, sustainable tools that can be implemented and evaluated to determine the extent to which they contribute to the increase in minority participation in NIH sponsored research and increase the self-efficacy of investigators dedicated to this goal.