COST-EFFECTIVENESS MODELING CORE

为了做出明智的预防资源分配决策，公共卫生决策者需要 关于成本、成本效益和各种预防战略的潜在影响的详细信息 艾滋病毒和其他性病的传播。成本效益建模核心支持科学研究， 艾滋病/性病预防干预的成本、经济效率和效果，相关行为 修改程序，干预传播和技术转让活动。核心提供 就进行经济效率或建模的可行性向CAIR调查员进行咨询 对拟议的、正在进行的或已完成的艾滋病毒预防和传播/技术转让干预措施进行研究。 核心科学家验证适当的经济评估或数学建模技术， 成本效益的干预，并与其他CAIR科学家合作，设计合适的 行为测量和成本数据收集工具，以支持经济评估研究， 建模研究。核心科学家在执行这些分析中发挥主导作用。核心的支持激活了 包括正在进行的干预试验过程中获得的前瞻性成本数据;回顾性数据 试验完成后的收集;量化干预有效性的临床建模， 流行病学上有意义的单位（例如，避免的HIV感染或预期的继发感染数量）; 和/或成本效益、成本效用或其他经济分析，以确定总体经济效率 艾滋病预防干预措施。

To make informed prevention resource allocation decisions, public health decision makers require detailed informafion about the cost, cost-effecfiveness, and potential impact of various strategies to prevent transmission of HIV and other STDs. The Cost-Effecfiveness Modeling Core supports scientific research into the cost, economic efficiency, and effectiveness of HIV/STD prevention intervenfions, related behavioral modificafion programs, and intervenfion disseminafion and technology transfer activifies. The Core provides consultafion to CAIR Investigators regarding the feasibility of conducting economic efficiency or modeling studies of proposed, ongoing, or completed HIV prevention and disseminafion/technology transfer interventions. Core Scientists idenfify appropriate economic evaluafion or mathemafical modeling techniques for assessing the cost-effectiveness ofthe intervention and collaborate with other CAIR Scienfists on the design of suitable behavioral measurement and cost data collecfion instruments to support economic evaluation research and modeling studies. Core Scienfists take a lead role in performing these analyses. The Core's support activifies include prospective cost data elicitafion during the course of an ongoing intervenfion trial; retrospective data collection after a trial is complete; mathemafical modeling to quantify intervenfion effectiveness in epidemiologically-meaningful units (e.g., HIV infecfions averted or expected number of secondary infecfions); and/or cost-effectiveness, cost-ufility, or other economic analyses to determine the overall economic efficiency of HIV prevenfion interventions.