P30 - CORE GRANT FOR VISION RESEARCH

描述（由申请人提供）：伊利诺伊大学芝加哥分校（UIC）视觉科学研究项目得到了美国国家眼科研究所（NEI）持续时间最长的核心资助之一的支持。核心补助金的总体目标是促进、加强和扩大UIC和邻近机构的视觉相关研究。核心基金的一个主要优势是它促进了UIC视觉科学研究社区（VSRC）之间的跨学科、跨部门和跨大学合作。目前的VSRC成员包括24名nih资助的研究者，他们在UIC眼科和视觉科学系有初级或二级职位，以及4名来自邻近芝加哥地区医学院的nei资助的研究者。在NIH资助的28名VSRC研究人员中，有19名获得了nei资助的资助（其中14名是合格的R01或K资助，由13名关键人员持有）。在这次续期提交中，核心赠款的模块化组织得到保留。单元由nei资助的研究人员指导，他们与经验丰富的技术人员一起提供无法由个人研究补助金支持的服务。四个核心资助模块是：(i)成像和图像分析模块，（ii）细胞和分子生物学模块，（iii）仪器车间模块和（iv）动物服务模块。这些模块将在以下领域提供设备齐全的设施和技术专长：数字图像采集和处理；图像分析;细胞生物学;组织学;分子生物学;生物化学;生物仪器的设计、生产和维护；还有动物服务。四个模块的设施总面积为3640平方米。UIC和邻近机构的视觉科学家很容易获得。核心基金将促进资源共享、思想交流和合作，满足VSRC研究人员对尖端生物仪器和技术专业知识的共同需求，并促进创新、跨学科和转化研究项目。

DESCRIPTION (provided by applicant): The University of Illinois at Chicago (UIC) vision science research program is supported by one of the longest-running core grants from the National Eye Institute (NEI). The overarching goal of Core Grant is to foster, strengthen and expand vision-related research at UIC and neighboring institutions. A major strength of the Core Grant is that it facilitates interdisciplinary, inter-departmental, and inter-university collaborations among UIC Vision Science Research Community (VSRC). Current VSRC members include 24 NIH-funded investigators who have primary or secondary appointments in the UIC Department of Ophthalmology and Visual Sciences, as well as 4 NEI-funded investigators from neighboring Chicago area medical schools. Of the 28 NIH funded VSRC investigators, 19 have NEI-funded grants (of which 14 are qualifying R01 or K grants, held by 13 Key Personnel). In this renewal submission the Modular organization of the Core Grant has been retained. Modules are directed by NEI-funded investigators who, together with experienced technical staff, provide services that cannot be supported otherwise by individual research grants. The four Core Grant modules are: (i) Imaging and Image Analysis Module, (ii) Cellular and Molecular Biology Module, (iii) Instrument Shop Module, and (iv) Animal Services Module. These modules will provide well-equipped facilities and technical expertise in the following areas: digital image acquisition and processing; image analysis; cellular biology; histology; molecular biology; biochemistry; design, production and maintenance of bioinstrumentation; and animal services. Together, the facilities of the four modules occupy 3,640 sq. ft. and are readily accessible to vision scientists at UIC and neighboring institutions. Fostering an environment conducive to resource-sharing, exchange of ideas and collaboration, the Core Grant will fulfill the common needs of VSRC researchers for cutting-edge bioinstrumentation and technical expertise and promote innovative, interdisciplinary and translational research programs.