Biomechanics of Upper Extremity function following Stroke.

描述（由申请人提供）： 摘要中风是美国成年人慢性残疾的最常见原因，65%的中风后患者不能将偏瘫上肢纳入日常功能。中风后即使是上肢功能的轻度损害也会导致日常功能的严重限制，并已被证明会对健康相关的生活质量产生负面影响。本研究的主要目的是确定生物力学变量，预测在家里的手臂使用量。将在实验室中测量上肢在伸手和抓握任务期间的运动学和动力学，并将使用便携式加速度计、运动活动日志和经验采样方法评估手臂在家庭环境中的使用量。我们将确定手臂和手部运动性能的特点，最好的预测显着的手臂使用在家里。 公共卫生相关性： 项目叙述中风是美国成年人慢性残疾的最常见原因，也是退伍军人的普遍状况。拟议项目旨在比较偏瘫手臂性能的实验室临床/生物力学测量与“真实的世界”环境中的实际手臂使用。了解实验室运动表现和家中手臂使用量之间的复杂关系将为如何最有效地进行治疗干预提供指导。拟议的工作有可能减少中风患者对VA和其他联邦机构的医疗保健负担，并改善他们的功能独立性和生活质量。

DESCRIPTION (provided by applicant): Abstract Stroke is the most common cause of chronic disability for adults in the United States, with 65% of individuals after stroke unable to incorporate the hemiparetic upper extremity into daily function. Even mild impairment of upper extremity function after stroke results in significant limitations in daily function and has been demonstrated to negatively impact health-related quality of life. The major objective of this study is to identify the biomechanical variables that predict amount of use of the arm at home. The kinematics and kinetics of the upper extremity during reaching and grasping tasks will be measured in the laboratory and the amount of use of the arm in the home environment will be assessed with portable accelerometry, Motor Activity Log and experience sampling methods. We will identify the characteristics of arm and hand motor performance that best predict significant arm use at home. PUBLIC HEALTH RELEVANCE: Project Narrrative Stroke is the most common cause of chronic disability for adults in the United States, and are a prevalent condition in Veterans. The proposed project intends to compare laboratory-based clinical/biomechanical measures of hemiparetic arm performance with actual arm use in the "real - world" setting. Understanding the complex relationship between laboratory motor performance and the amount of arm use at home will provide guidance on how to most efficiently target therapeutic interventions. The proposed work has the potential to decrease the health care burden placed on the VA and other Federal agencies by stroke patients and to improve their functional independence and quality of life.