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简介(申请人提供):5-羟色胺俱乐部成立于1987年,是一个由对神经递质5-羟色胺任何方面的研究感兴趣的生物医学科学家组成的国际协会。5-羟色胺仍然是研究的重点,对药物滥用、疼痛、心血管功能、消化过程,特别是精神健康具有重要意义。影响5-羟色胺能神经传递的药物被用于治疗重度抑郁症、精神分裂症、躁狂、焦虑、进食障碍、恐慌和创伤后应激障碍。5-羟色胺俱乐部每隔一年主办一次关于5-羟色胺的国际会议,并举办与美国神经科学学会会议相关的年度讲座和晚宴。2010年5-羟色胺俱乐部会议将于7月9日至11日在蒙特利尔举行。该俱乐部的总体目标是举办一次关于5-羟色胺研究的国际会议,该会议将具有尽可能高的科学质量,以吸引和教育年轻和高级研究人员。2010年会议计划的一个创新特点是增加了一名初级科学家,从提交的摘要中挑选出来,在每次研讨会上发言。R13申请的主要目的是为学生、博士后研究员和初级研究人员(即不超过博士后培训三年的年轻研究人员)提供财政支持,使他们能够出席和参加2010年5-羟色胺俱乐部会议。奖学金将分两个级别提供:1.将向12名年轻调查人员(即。学生、博士后研究员、初级研究人员),被选为12个专题讨论会中每一个专题讨论会的第四位发言者。该奖项将支付参加研讨会的每名青年调查人员的注册费、机票、住房和生活费;2.杰出摘要奖将颁发给10名年轻调查人员(即。学生、博士后研究员、初级研究员)。这些奖励将为这些年轻的研究人员支付注册费和参加会议的部分费用。旅行奖和杰出摘要奖的目的是支持年轻研究人员出席5-羟色胺俱乐部会议。这些奖项的目的是鼓励青年研究人员通过接触5-羟色胺俱乐部成员和会议上介绍的科学来参与和职业发展。参加5-羟色胺俱乐部会议的机会将促进年轻科学家的职业生涯,使他们有机会(I)参与一个杰出的科学计划,(Ii)了解5-羟色胺研究的最新进展,以及(Iii)与他们以前仅通过文献了解的国际知名研究人员和科学家见面和互动。5-羟色胺俱乐部认识到指导对初级科学家职业发展的重要性。所有获奖者都将参加导师计划。指导计划为年轻研究人员提供了接触更有经验的研究人员的正式机会。 公共卫生相关性:5-羟色胺研究对物质滥用、疼痛、心血管系统、消化过程,特别是精神健康很重要。5-羟色胺能药物用于治疗抑郁症、精神分裂症、躁狂、焦虑、进食障碍、恐慌和创伤后应激障碍。通过支持年轻科学家出席5-羟色胺俱乐部会议,旅行和杰出摘要奖将促进青年科学家的职业生涯,使他们有机会(I)参与杰出的科学计划,(Ii)了解5-羟色胺研究的最新进展,以及(Iii)与他们以前仅通过文献了解的国际知名研究人员见面和互动。
英文摘要
DESCRIPTION (provided by applicant): The Serotonin Club, founded in 1987, is an international association for biomedical scientists who are interested in research on any aspect of the neurotransmitter serotonin. Serotonin continues to be the focus for research important to substance abuse, pain, cardiovascular function, digestive processes, and especially mental health. Drugs that influence serotonergic neurotransmission are used to treat major depression, schizophrenia, mania, anxiety, eating disorders, panic, and post-traumatic stress disorder. The Serotonin Club sponsors an international meeting on serotonin every other year, and hosts annual lectures and dinners held in association with the American Society for Neuroscience meeting. The Serotonin Club Meeting for 2010 will be held July 9-11 in Montreal. The Club's overall goal is to conduct an international meeting on serotonin research that will be of the highest possible scientific quality in order to attract and educate both young and senior investigators. An innovative feature of the 2010 Meeting program is the addition of one junior scientist, selected from submitted abstracts, to speak per symposium. The primary aim of this R13 application is to provide financial support to students, post-doctoral fellows and junior researchers (i.e. young investigators not more than three years past their postdoctoral period of training) to enable them to attend and participate in the 2010 Serotonin Club Meeting. Bursaries will be provided at two levels: 1. Travel Awards will be given to 12 young investigators (ie. students, post-doctoral fellows, junior researchers), chosen to be featured as the fourth speaker in one of each of the 12 symposia. The award will cover the registration fee, airfare, housing and subsistence costs for each of the young investigators participating in the symposia; 2. Outstanding Abstract Awards will be given to 10 young investigators (ie. students, post-doctoral fellows, junior researchers). These awards will cover the registration fee and a portion of expenses to attend the meeting for these young researchers. The purpose of the Travel Awards and the Outstanding Abstract Awards is to support the attendance of young investigators at the Serotonin Club Meeting. The objective of these Awards is to encourage the involvement and career development of young researchers through their exposure to the members of the Serotonin Club and science presented at the Meeting. The opportunity to attend the Serotonin Club Meeting will foster the careers of young scientists by affording them the opportunity to (i) participate in an outstanding scientific program, (ii) learn the most recent, and often unpublished, advances in serotonin research, and (iii) meet and interact with internationally distinguished researchers and scientists with whom they had previously known only through literature. The Serotonin Club recognizes the importance of mentoring to the professional development of junior scientists. All awardees will participate in the Mentorship Program. The Mentoring Program provides formal opportunities for young investigators to benefit from access to more experienced researchers. PUBLIC HEALTH RELEVANCE: Serotonin research is important to substance abuse, pain, cardiovascular systems, digestive processes, and especially mental health. Serotonergic drugs are used to treat depression, schizophrenia, mania, anxiety, eating disorders, panic, and post-traumatic stress disorder. By supporting the attendance of young scientists to the Serotonin Club Meeting, Travel and Outstanding Abstract awards will foster the careers of young scientists by affording them the opportunity to (i) participate in an outstanding scientific program, (ii) learn about the most recent advances in serotonin research, and (iii) meet and interact with internationally distinguished researchers with whom they had previously known only through literature.
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Increased vulnerability of BDNF deficient mice to mild stress
Increased vulnerability of BDNF deficient mice to mild stress
5HT transporter & 1A receptor function in BDNF(+/-)mice
5HT transporter & 1A receptor function in BDNF mice
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