2010 Ion Channels GRC

描述（由申请人提供）： 该提案要求部分支持国际参加的离子通道会议，作为戈登研究会议系列的一部分，将于2010年7月11日至16日在新罕布什尔州蒂尔顿的蒂尔顿学校举行。会议的广泛和长期目标是增加我们对离子通道的基本结构，功能和生理作用的理解，以及它们在疾病，特别是神经系统疾病中的功能障碍。本次会议的具体目标是召集代表离子通道研究关键领域的42位发言人和讨论负责人，共有135名与会者在相对隐蔽的环境中举行为期五天的会议。该计划将有九个会议，广泛解决离子通道机制和生理学的当前问题。此外，四场海报会议将使所有与会者能够就这些专题发表意见。这项应用的意义在于，离子通道戈登研究会议是既定会议的一个重要组成部分，这些会议丰富了离子通道生物学家国际社会的想法和研究。事实上，离子通道研讨会规模小，讨论激烈，这使得它对参与者中新思想和新方向的催化作用具有独特的重要性。这种应用的健康相关性在于，讨论将确定在影响人类发展和健康的各种领域中需要实验解决的问题。 公共卫生相关性：该应用程序的相关性在于，尖端研究的详细讨论将定义在影响人类发育的领域需要实验解决的问题，以及几乎每个组织和器官系统的兴奋性障碍，包括中枢神经系统，感觉器官，胰腺，心脏，平滑肌和骨骼肌。这些问题也将与人类衰老直接相关。最终，这些问题的定义和实验解决方案将为各种人类疾病的创新治疗方法铺平道路。

DESCRIPTION (provided by applicant): This proposal requests partial support for an internationally attended meeting on Ion Channels, as part of the Gordon Research Conference series, to be held at the Tilton School in Tilton, New Hampshire, July 11-16, 2010. The broad and long-term goal of the conference is to increase our understanding of the fundamental structure, function and physiological roles of ion channels as well as their dysfunction in disease, particularly neurological disorders. The specific aims of this meeting will be to convene 42 speakers and discussion leaders that represent critical areas of ion channel research with a total of 135 participants for a five-day meeting in a relatively secluded setting. The program will have nine sessions that broadly address current issues in ion channel mechanisms and physiology. In addition, four poster sessions will permit all participants to contribute their work to these topics. The significance of this application is that the Ion Channels Gordon Research Conference is a critical component of the established meetings that fertilize ideas and research in the international community of ion channel biologists. Indeed, the small size and intensive discussions engendered by the Ion Channels GRC make it uniquely important for the catalysis of new ideas and directions among the participants. The health relatedness of this application is that the discussions will define questions that require experimental resolution in a wide variety of areas that affect human development and health. PUBLIC HEALTH RELEVANCE: The relevance of this application is that the detailed discussions of cutting edge research will define the questions that require experimental resolution in areas that affect human development, and excitability disorders of almost every tissue and organ system, including the central nervous system, sensory organs, the pancreas, cardiac, smooth and skeletal muscle. These questions will also be directly relevant to human aging. Ultimately, the definition and experimental resolution of these issues will pave the way for innovative therapeutic approaches to a wide variety of human diseases.