课题基金 / 基金详情

Innate Discovery Team

Innate Discovery Team
先天探索团队
批准号：
8294657
负责人：
Nina Bhardwaj
金额：
$120.4万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-07-01 至 2013-06-30
来源：
https://reporter.nih.gov/project-details/8294657
关键词：
AIDS/HIV problemActivities of Daily LivingAcuteHIV InfectionsImmunologyIn VitroIndividualInfectionPeripheral Blood Mononuclear CellPhasePropertyRelative (related person)Resistance to infectionVaccinesinnate immune functioninsightperipheral blood

项目摘要

项目成果

Nina Bhardwaj的其他基金

相似基金

相关文献

中文摘要
翻译
1.具体目标 整个先天扩建工程的具体目标是： 1.检测慢性阻塞性肺疾病早期患者外周血中NK、DC亚群的功能 急性艾滋病毒感染(AMI)，为了深入了解感染关键初始阶段的先天免疫功能， 二、分析欧盟和解脲支原体患者外周血中NK和DC亚群的功能特性。 确定与欧盟地位相关的先天亚群的功能/相互作用的保护性方面。 三、比较欧盟和解脲支原体患者外周血单个核细胞(PBMC)对 支持艾滋病毒在体外的感染，并研究相对感染耐药的机制。
英文摘要
1. Specific aims The specific aims of the entire innate expansion project are: 1. To characterise the functional capacity of peripheral blood NK and DC subsets during the earliest phase of acute HIV infection (AMI), to gain insight into innate immune functions in the critical initial phase of infection, ii. To analyse the functional properties of peripheral blood NK and DC subsets in EU and UU individuals, to identify protective aspects of the functions/interaction of innate subsets associated with EU status. iii. To compare the capacity of peripheral blood mononuclear cells (PBMCs) from EU and UU individuals to support HIV infection in vitro, and investigate the mechanisms underlying relative resistance to infection.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
The Tisch Cancer Institute (TCI) Paul Calabresi K12 Career Development Award for Clinical Oncology
The Tisch Cancer Institute (TCI) Paul Calabresi K12 Career Development Award for Clinical Oncology
Dissecting myeloid cell-mediated resistance to immune checkpoint blockade in bladder cancer
Dissecting myeloid cell-mediated resistance to immune checkpoint blockade in bladder cancer
海外基金