International Training in AIDS/TB Prevention Research

描述（由申请人提供）：这个国际艾滋病研究培训项目以印度为主要重点国家，卢旺达和孟加拉国为次要国家。我们的目标是在这些国家开展艾滋病毒/艾滋病、结核病和艾滋病真菌病原体领域的研究能力建设。为此，我们建议培训这些国家的科学家掌握关键的生物医学、流行病学和行为研究方法。还提供血液安全和临床研究方面的辅助培训。我们的培训模式包括短期、中期和长期培训。短期培训将通过为期10天的讲习班在国内进行（主要在印度举行，但由所有三个国家的受训人员参加，有时在卢旺达为该国的受训人员参加），这些讲习班旨在培训特定艾滋病毒/艾滋病领域的临床医生和基础研究人员。3-6个月的中期培训是我们的核心培训模式，包括培训在印度或孟加拉国注册进行艾滋病主题论文研究的研究生访问阿尔伯特爱因斯坦，研究涉及（但不限于）：当地艾滋病毒亚型的特征；艾滋病患者痴呆可能差异发生率的基础HIV耐药及其检测制定艾滋病预防方法及其疗效评价；妇女对HAART治疗态度的流行病学研究；新生假丝酵母菌和念珠菌的诊断研究进展艾滋病真菌条件致病菌的分子生物学及发病机制研究快速、廉价的基于噬菌体的结核分枝杆菌检测方法和研究结核分枝杆菌基因作用的遗传学方法。我们的长期培训包括两个部分：临床研究培训计划（CRTP）的硕士学位和艾滋病研究的博士后研究培训。虽然短期和长期培训涵盖所有三个国家，但美国中期培训最初侧重于印度和孟加拉国。对于卢旺达，我们还建议在国内进行流行病学培训。我们培训计划的一个重要组成部分是确保学员回国，方法是在中途培训研究生，确保他们回国并分享专业知识，选择有长期固定职位的学员，帮助他们在生物医学研究机构找到职位，并通过为符合条件的个人提供先进的国内研究项目支持。

DESCRIPTION (provided by applicant): This international AIDS research training program has India as its major country of focus and Rwanda and Bangladesh as minor countries. Our goal is research capacity-building in these countries in the areas of HIV/AIDS, tuberculosis and fungal pathogens of AIDS. To this end, we propose to train scientists from these countries in critical biomedical, epidemiological and behavioral research methodologies. Accessory training in blood safety and clinical research is also provided. Our training models include short, medium and long- term training. Short-term training will be in-country (to be held mostly in India but attended by trainees in all three countries and sometimes in Rwanda for trainees in that country) via 10-day workshops aimed at specialized topics aimed at training clinicians and basic researchers in specific HIV/AIDS areas. Medium- term training for 3-6 months is our core training model involving training of graduate students registered for thesis research in AIDS topics in India or Bangladesh visiting Albert Einstein for research involving (but not limited to): Characterization of local subtypes of HIV; Basis for possible differential incidence of dementia in AIDS; Drug resistance in HIV and its detection; Developing AIDS prevention methods and the evaluation of their efficacy; Epidemiological studies on attitudes of women to HAART; Development of diagnostics for C. neoformans and Candida sp.; Molecular biology and pathogenesis of fungal opportunistic pathogens of AIDS; Rapid, inexpensive phage-based detection methods for M. tuberculosis and Genetic approaches to study role of M. tuberculosis genes. Our long-term training consists of two components: a Master's degree in Clinical Research Training Program (CRTP) and Post-doctoral research training both in AIDS research. While the short-term and the long-term training covers all three countries, the medium-term US training is initially focused on India and Bangladesh. For Rwanda, we also propose in-country training in epidemiology. An important element of our training plan is ensuring the return of the trainees to their home countries by training graduate students in mid-stream which ensures their return and sharing of expertise, selecting long- term trainees with prior permanent positions as well as assisting them find positions in biomedical research organizations as well as via Advanced in-country research project support for eligible individuals.