Bioiron 2011: From basic science to medicine

描述（由申请人提供）：我们正在申请资金，以帮助支持2011年5月22日至5月26日在加拿大温哥华举行的Bioiron 2011会议。我们预计有450-500名参与者，其中2/3将是年轻的研究者。这些资金将用于资助20名年轻的美国研究人员、博士后和学生参加会议，他们将根据杰出的摘要选出。这项投资的目的是促进美国对铁相关疾病的病因、诊断和治疗的研究。获奖者将由全球铁生物学领域的顶尖科学家组成的组委会选出。年轻研究人员将被定义为40岁以下的科学家，他们没有担任过ro1型资助或同等财政资助的主要研究人员。生物铁会议是全面介绍和讨论铁生物学、铁相关疾病（铁超载失调、铁限制性贫血等）以及与这些疾病相关的诊断和治疗的前沿进展的主要国家和国际论坛。该会议每两年举行一次，轮流在铁生物学研究项目最活跃、能提供合适会议设施的大洲和国家举行。2011年Bioiron的组织者致力于确保来自世界各地的科学家的广泛参与，无论其国籍、性别、种族或其他个人特征。与健康相关的铁生物学方面将是2011年会议的首要任务。在规划本次会议时，特别考虑了NIH和NIDDK的优先事项。除了对最先进的铁病理生物学的广泛概述外，2011年的项目还将特别强调我们对分子铁传感、细胞内铁转运、铁调控（包括hepcidin、铁转运蛋白和microrna）、铁负荷贫血中铁超载的发病机制、遗传性血色素沉着症和铁缺乏的遗传学、局部铁稳态紊乱以及铁的诊断和治疗方面的最新进展。

DESCRIPTION (provided by applicant): We are requesting funds to help support the Bioiron 2011 Conference in Vancouver, Canada, scheduled for May 22 to May 26, 2011. We expect 450-500 participants of whom 2/3 will be young investigators. The funds will be used to subsidize conference participation by twenty young US investigators, post-doctoral fellows and students, selected on the basis of outstanding abstracts. The objective of this investment is to advance research on the causes, diagnosis and treatment of iron-related diseases in the US. The awardees will be selected by the Organizing Committee consisting of the leading scientists in the field of iron biology worldwide. Young investigators will be defined as scientists under 40 who have not acted as principal investigators on an RO1-type grant or its financial equivalent. The Bioiron conference is the main national and international forum for comprehensive presentation and discussion of cutting-edge advances in iron biology, iron-related diseases (iron overload disorders, iron-restrictive anemias, and others), and diagnostics and therapies related to these diseases. The conference has taken place every two years, rotating between continents and countries that have the most active research programs in iron biology and can provide suitable conference facilities. The organizers of Bioiron 2011 are committed to assuring broad participation by scientists from all over the world regardless of national origin, gender, race or other personal characteristics. The health- related aspects of iron biology will be the primary priority of the 2011 conference. NIH and NIDDK priorities are specifically taken into account in planning this conference. In addition to a broad overview of state-of-the-art iron pathobiology, the 2011 program will specifically highlight recent advances in our understanding of molecular iron sensing, intracellular iron transport, iron regulation including by hepcidin, ferroportin and microRNAs, pathogenesis of iron overload in iron-loading anemias, genetics of hereditary hemochromatosis and iron deficiency, localized disorders of iron homeostasis, and iron diagnostics and therapeutics. PUBLIC HEALTH RELEVANCE: We are requesting funds to help support the Bioiron 2011 Conference in Vancouver, Canada, scheduled for May 22 to May 26, 2011. The funds will be used to facilitate conference participation by twenty young US investigators, post-doctoral fellows and students, selected on the basis of outstanding abstracts. The expected public health impact of this investment is to advance research on the causes, diagnosis and treatment of iron- related diseases in the US.