2011 Chronobiology Gordon Research Conference

描述（由申请人提供）：我们要求为第17届时间生物学戈登研究会议提供部分支持，该会议将于2011年6月12日至17日在意大利巴尔加举行。会议将集中讨论代表时间生物学关键研究领域的主题，包括分子生物学、遗传学、行为（包括睡眠）、神经生物学、代谢、癌症和（健康）衰老。因此，会议的副主题将是“整合：从分子到有机体”。所有的演讲者和讨论领导者都是各自领域公认的领导者，并且是在与代表时间生物学领域广度的科学家协商后选择的。特别注意文化多样性，暂定方案在性别平衡方面反映了这一点。我们已经成功地建立了一个非常高质量的项目，其中超过40%的演讲者和讨论领袖是女性。我们的目标是通过注册进一步提高多样性；将优先考虑代表性不足的群体的成员。传统上，培训方面以热点话题讲座的形式正式纳入该计划，这些讲座是为学生和博士后研究员保留的。会议的具体目标是：1)为讨论最新（未发表的）时间生物学研究提供一个论坛。2)将主要研究时间生物学分子方面的科学家与那些关注更高层次组织的科学家，以及工业界的精选代表聚集在一起，整合从基础研究到应用研究的各个层面。3)通过识别知识差距和改进概念模型，确定未来几年的优先研究主题（如衰老、代谢、病理）。4)继续——正如时间生物学传统所要求的那样——为学员和资深研究人员之间的互动提供一个高质量和容易接近的场所。

DESCRIPTION (provided by applicant): We request partial support for the 17th Chronobiology Gordon Research Conference, to be held in Barga, Italy from June 12 - 17 in 2011. The conference will focus on topics that represent key research areas in chronobiology, which include molecular biology, genetics, behavior (including sleep), neurobiology, metabolism, cancer and (healthy) aging. The subtheme of the conference will thus be 'Integration: from molecule to organism'. All of the speakers and discussion leaders are recognized leaders in their fields and were chosen in consultation with scientists who represent the breadth of the field of chronobiology. Special attention has been given to cultural diversity and the tentative program reflects this in terms of gender balance. We have been successful in building an extremely high-quality program that features over 40% female speakers and discussion leaders. We aim to improve diversity further through registrations; preference will be given to members of under-represented groups. Training aspects have traditionally been formally incorporated into the program in the form of Hot Topic talks, which are reserved for students and post doctoral fellows. The specific objectives of the conference are: 1) to provide a forum for discussion of the latest (unpublished) chronobiology research. 2) to bring together scientists working primarily with molecular aspects of chronobiology with those who focus on higher levels of organization, as well as selected representatives of industry, to integrate across all levels - from fundamental to applied research. 3) to identify priority research themes for the coming years (e.g. aging, metabolism, pathologies) by identifying gaps in knowledge and improving conceptual models. 4) to continue - as chronobiology tradition dictates - to provide a high quality and accessible arena for interaction between trainees and senior researchers. PUBLIC HEALTH RELEVANCE: Chronobiology GRC 2011 Project narrative: The clock regulates a myriad of processes in organisms from all phyla. Recent discoveries showing robust circadian rhythms in virtually all cells emphasize the pervasive impact of the circadian clock on physiology and behavior. Accordingly, epidemiological and genetic studies on humans show that a disrupted circadian clock - whether due to genetic predisposition or to socially influenced behavior - leads to pathologies that are associated with aging in our society: sleep disorders, metabolic disease and obesity, and cancer, for example. This conference will bring together experts and trainees who are in a position to integrate and translate basic research into applied science and policy, renewing the focus of the chronobiology field to keep pace with the latest research results and the interests of society.