2011 Rachmiel Levine Diabetes and Obesity Symposium: Advances in Diabetes Biology

描述（由申请人提供）：2011年R13资助申请：每年，希望之城的糖尿病、内分泌和代谢部门都会举办一年一度的糖尿病研讨会，以纪念已故的Rachmiel Levine博士，他是一位科学家，负责识别人类胰岛素，这一重要发现已经帮助拯救了全世界数百万患者的生命，并继续用于今天的治疗。因此，莱文研讨会的使命是汇集国际领先的科学家，以及年轻的研究人员和学生，目的是汇集新的想法和知识，这将直接导致我们对抗、预防甚至治疗糖尿病的能力取得重大进展。在前几年，莱文研讨会计划全面涵盖了1型和2型糖尿病研究中最新和最重要的主题，每年有来自22个国家和美国30个州的近400名科学家，医生，研究员和学生参加。2011年的Rachmiel Levine研讨会，题为“糖尿病生物学、免疫学和细胞治疗的进展”，将于2011年3月20日至23日在加州帕萨迪纳的朗廷亨廷顿酒店举行，将重点讨论胰岛免疫学和炎症、β细胞再生和存活、糖尿病和癌症之间的联系，以及糖尿病的新技术，包括人工胰腺、体内胰岛成像和在胰岛移植中使用生物相容性设备。所有的报告都将联系1型和2型糖尿病的研究，并提供对该领域最新发展的见解。会议还将讨论更多有争议的话题，如人源化小鼠、病毒感染在1型糖尿病中的作用、调节性t细胞（及其在1型糖尿病中的潜在缺陷）。该项目还将包括最近的临床试验结果、胰岛生物学技术研讨会和年轻研究人员的口头报告，以便与该领域更有经验的人进行更多的互动。海报会议和主题晚宴演讲将完成该计划。今年的会议预计将吸引来自美国和国外的知名科学家，内分泌学家，糖尿病学家，胰岛生物学家，干细胞和基因转移科学家，移植科学家，免疫学家，细胞生物学家，以及前面提到的所有领域的年轻研究人员，以及参与糖尿病患者管理的其他医疗保健专业人员。

DESCRIPTION (provided by applicant): 2011 Rachmiel Levine Diabetes and Obesity Symposium R13 Grant Application Each year, the Department of Diabetes, Endocrinology and Metabolism at City of Hope holds an annual diabetes symposium named in honor of the late Dr. Rachmiel Levine, the scientist responsible for identifying human insulin-a vital discovery that has already helped save the lives of millions of patients around the world, and continues to be used in treatment today. Thus, the Levine Symposium is charged with the mission of bringing together leading international scientists, as well as young investigators and students, for the purpose of pooling new ideas and knowledge that will directly lead to major advances in our ability to fight, prevent, and even cure diabetes. In prior years, the Levine Symposium program has comprehensively covered the latest and most important topics in type 1 and type 2 diabetes research, with the highest annual attendance of nearly 400 scientists, physicians, fellows, and students from 22 countries and 30 U.S. states. The 2011 Rachmiel Levine Symposium, entitled "Advances in Diabetes Biology, Immunology, and Cell Therapy" will be held March 20-23, 2011 at The Langham Huntington Hotel in Pasadena, California, and will highlight topics in islet immunology and inflammation, beta cell regeneration and survival, the link between diabetes and cancer, and new technologies in diabetes, including the artificial pancreas, in vivo islet imaging, and use of biocompatibility devices in islet transplantation. All presentations will link type 1 and type 2 diabetes research, and provide insight into the most recent developments in the field. The meeting will also feature debates on more controversial topics, such as the humanized mouse, the role of virus infection in type 1 diabetes, and regulatory T-cells (and their underlying defects in type 1 diabetes). The program will also include the results of recent clinical trials, technical workshops in islet biology, and oral presentations from young investigators to allow for greater interaction with those more experienced in the field. A poster session and a keynote dinner lectureship will complete the program. This year's meeting is expected to attract from both the U.S. and abroad, as it has in the past, well-established scientists, endocrinologists, diabetologists, islet biologists, stem cell and gene transfer scientists, transplant scientists, immunologists, cell biologists, as well as young investigators in all of the previously mentioned fields, in addition to other health care professionals involved in the management of patients with diabetes.. PUBLIC HEALTH RELEVANCE: 2011 Rachmiel Levine Diabetes and Obesity Symposium R13 Grant Application The 11th Annual Rachmiel Levine Diabetes and Obesity Symposium will continue to offer investigators a state- of-the-art, comprehensive scientific forum of international caliber and scope by covering topics in islet immunology and inflammation, beta cell regeneration and survival, the links between diabetes and cancer, and new technologies in diabetes, including the artificial pancreas, in vivo islet imaging, and use of biocompatibility devices in islet transplantation. The meeting will also present debates on the latest controversial topics, including the humanized mouse, the role of virus infection in type 1 diabetes, and regulatory T-cells (and their underlying defect(s) in type 1 diabetes). Additionally, workshops will be offered on methods of islet preparation and quality testing. In the past, the Symposium has represented an invaluable source of knowledge sharing for the scientific and medical communities involved in diabetes and obesity research and care, and it will continue to promote new interactions and collaborations among young scientists and established leaders in the future.