CLINICAL TRIAL: BIOLOGY AND USE OF TNF INHIBITION IN CHILDREN WITH JUVENILE IDIO

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究提案将首次提供多关节和扩展性寡聚幼年特发性关节炎患者中持续非活动性疾病和发作的频率和时间数据，这些患者在停用抗TNF治疗后表现出良好的临床应答。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study proposal will be the first to provide data on the frequency and timing of both continued inactive disease and flare in patients with polyarticular and extended oligo juvenile idiopathic arthritis who have demonstrated an excellent clinical response upon withdrawal of the anti-TNF therapies.