CONDUCTING PUBLIC HEALTH RESEARCH IN TAILAND BY THE MINISTRY OF PUBLIC HEALTH (MO

描述（由申请人提供）：本研究是多国病例对照研究的一部分，旨在确定世界卫生组织定义的5岁以下儿童重症和极重症肺炎的原因和风险因素。这项研究由比尔和梅林达盖茨基金会资助，并由约翰霍普金斯大学公共卫生学院的一个研究小组协调。预计将进行研究的地点将代表2015年大多数儿童重症肺炎病例将发生的地区，以及预计从2015年起将广泛采用的关键干预措施已经到位的地区。 已选定的七个生境中心地点包括南非约翰内斯堡、赞比亚卢萨卡、肯尼亚基利菲、冈比亚巴塞、马里巴马科、孟加拉国达卡和泰国萨凯奥和那空帕诺姆。 在泰国，该研究将通过公共卫生部和国际新发感染项目（lEIP）在两个mral省（萨凯奥和那空府帕诺姆）的合作实施。萨凯奥位于泰国东部，与柬埔寨接壤，人口537，000（32，000名5岁以下儿童）。Nakhon帕诺姆在泰国东北部与老挝接壤，有742，000居民（48，000年龄<5）。2007年，萨凯奥省的人均年国内生产总值为997美元，那空帕诺姆省为1 006美元（2007年资料）。PERCH研究将在各省的省级医院进行。

DESCRIPTION (provided by applicant): This study is part of a multi-country case-control study to determine causes of and risk factors for severe and very severe pneumonia among children <5 years of age, as defined by the World Health Organization. The study is funded by the Bill & Melinda Gates Foundation and coordinated by a research team at the School of Public Health, Johns Hopkins University. The sites where the study will be conducted are projected to be representative of the areas where most of the severe pneumonia cases in children will occur in 2015 and where key interventions that are expected to be widespread from 2015 onwards are already in place. Seven PERCH sites that have been selected include Johannesburg, South Africa , Lusaka, Zambia, Kilifi, Kenya, Basse, the Gambia, Bamako, Mali, Dhaka, Bangladesh and Sa Kaeo and Nakhon Phanom, Thailand. In Thailand, the study will be implemented through a collaboration between Ministry of Public Health and the Intemational Emerging Infections Program (lEIP) in two mral provinces: Sa Kaeo and Nakhon Phanom. Sa Kaeo province is in eastem Thailand on the Cambodian border and has a population of 537,000 (32,000 age <5 years). Nakhon Phanom borders Laos in northeastem Thailand and has 742,000 residents (48,000 age <5). The 2007 per capita annual GDP was $997 in Sa Kaeo province and $1,006 in Nakhon Phanom province (Information 2007). The PERCH study will be conducted in the provincial hospitals in each province.