Institutional Research Cancer Epidemiology Fellowship

描述(由申请人提供)：本申请是为约翰霍普金斯大学彭博公共卫生学院癌症流行病学、预防和控制培训计划的NRSA机构研究补助金续期5年(29-33年)。该计划的使命是培养博士后学生和博士后研究员，使他们成为前沿的领导者，促进a)癌症原因的知识，以及b)如何通过更好地了解癌症相关行为和确定早期发现癌症的新标记物来预防癌症。该计划的目标是为受训者创造一个丰富的互动环境，并通过由公共卫生与医学院和坎摩尔癌症中心的观察性、基础性和临床科学家进行的高度创新、富有成效和协作的癌症研究来加强。该计划有3个培训轨道：1)癌症病因和预防，包括转化研究；2)癌症遗传流行病学，包括基因组学和表观遗传学；以及3)癌症控制，包括差异、沟通和烟草。6名博士后和3名博士后受训人员参加了一项重点课程，其中包括各个领域的共同要素：实质性和方法论主题以及研究伦理的教学课程；互动信息交流；教学、交流、论文撰写经验；博士后或博士后研究；以及针对具体项目的教育、研究和职业指导。强调了开发和测试新的假设以及跨学科合作的重要性。通过共享的元素，学员接触到当前的主题，如转化研究、分子流行病学、癌症新出现的风险因素、癌症研究和筛查中的方法学问题、差异、沟通、烟草控制、肥胖、炎症，以及在风险评估和公共政策中使用流行病学。19位公认的导师根据他们的教学、建议和研究记录而被挑选出来，负责初级指导。另有34个附属学院为学员提供特定癌症部位、生物统计学和基于实验室的暴露评估方面的尖端专业知识。指导委员会负责学员的选择和监测，并随着基于人群的癌症研究的发展而完善项目。培训期限一般为4-5年，博士后学员为2年。该项目在培训和指导方面有着很好的记录：在过去10年中任命的26名博士后和14名博士后实习生都接受过癌症研究培训，并取得了职业成功。从大量的申请者中，招聘可能最好的应聘者。受训者代表不同的背景；该计划是3种治疗补充剂的接受者。总而言之，培训计划旨在a)为学员提供进行最高水平、最先进的、协作的、可转化的癌症研究所必需的多学科背景，b)培养他们成为创新的思考者，c)发展他们的教学和沟通技能，以及d)使他们准备成为国家癌症研究议程的领导者。 公共卫生相关性：该培训计划与美国和全世界的癌症负担直接相关。这个项目的使命是培养博士后学生和博士后研究员，使他们成为前沿的领导者，以促进a)癌症的原因，包括内在和可改变因素的知识，以及b)如何通过更好地了解癌症相关行为和确定新的癌症早期检测标记物来预防癌症。该计划将培训学员培养成下一代以人口为基础的研究人员，他们将制定和处理国家的癌症研究议程，目标是减少癌症的发病率、发病率、复发率和死亡率，以及癌症之间的差异。

DESCRIPTION (provided by applicant): This application is for the 5-year renewal (Years 29-33) of an NRSA Institutional Research Grant for the training program in Cancer Epidemiology, Prevention, and Control at the Johns Hopkins Bloomberg School of Public Health. The program mission is to train pre-doctoral students and post-doctoral fellows to become leaders at the forefront of advancing the knowledge of a) the causes of cancer, and b) how to prevent it by providing a better understanding of cancer-related behaviors and identifying new markers for the early detection of cancer. The program goal is to create a rich and interactive environment for trainees augmented by the highly innovative, productive, and collaborative cancer research conducted by observational, basic, and clinical scientists at the Schools of Public Health and Medicine and the Kimmel Cancer Center. The program has 3 training tracks: 1) Cancer Etiology and Prevention, including translational research; 2) Genetic Epidemiology of Cancer, including genomics and epigenetics; and 3) Cancer Control, including disparities, communication, and tobacco. The 6 pre- and 3 post-doctoral trainees pursue a focused program consisting of shared elements across the tracks: didactic courses on substantive and methodologic topics and research ethics; interactive information exchange; teaching, communication, grant writing experiences; pre- or post- doctoral research; and program-specific education, research, and career mentoring. The importance of developing and testing novel hypotheses and collaborating across disciplines is stressed. Via the shared elements, the trainees are exposed to current topics, such as translational research, molecular epidemiology, emerging risk factors for cancer, methodologic issues in cancer research and screening, disparities, communication, tobacco control, obesity, inflammation, and use of epidemiology in risk assessment and public policy. Nineteen established preceptors, selected based on their records of teaching, advising, and research, are responsible for primary mentoring. An additional 34 affiliated faculty provide the trainees with cutting-edge expertise in specific cancer sites, biostatistics, and laboratory-based exposure assessment. The steering committee is responsible for trainee selection and monitoring, and program refinement as population-based research on cancer evolves. Training duration is typically 4-5 years for pre- and 2 years for post-doctoral trainees. The program has a strong record of training and mentorship: the 26 pre- and 14 post-doctoral trainees appointed in the past 10 years have cancer research training and career success. From a large pool of applicants, the best possible candidates are recruited. The trainees represent diverse backgrounds; the program is the recipient of 3 CURE supplements. In summary, the training program is designed to a) provide trainees with the multidisciplinary background essential to conduct the highest caliber, state-of-the-art, collaborative, translational cancer research, b) nurture them to be innovative thinkers, c) develop their teaching and communication skills, and d) prepare them to be leaders of the nation's cancer research agenda. PUBLIC HEALTH RELEVANCE: The training program is directly relevant to the burden of cancer in the US and throughout the world. The mission of this program is to train pre-doctoral students and post-doctoral fellows to become leaders at the forefront of advancing the knowledge of a) the causes of cancer, including inherent and modifiable factors, and b) how to prevent cancer by providing a better understanding of cancer-related behaviors and identifying new markers for the early detection of cancer. The program prepares trainees to be the next generation of population-based researchers who will set and address the nation's cancer research agenda with the goal of reducing cancer incidence, morbidity, recurrence, and mortality, and the disparities in cancer.