Developmental Research Program

认识到发展研究基金是SPORE的一个组成部分，我们承诺每 这些年的努力。这在UM前列腺SPORE的预算中占很大比例， 反映了该计划对创新转化研究发展的持续承诺， 前列腺癌发展研究计划（DRP）的重点是为研究人员提供 为提交R 01资助申请或同等提案生成初步数据的资源 鼓励来自前列腺癌领域以外的研究人员通过校园范围内的申请 公告以及通过与SPORE调查人员的个人互动。我们开发了一个 采用NIH类型PHS 398格式的试点项目的逐步提案征集和审查过程， 已被精简，以快速周转的研究建议，并承认这些项目可能有 一些初步数据。调查人员可以申请试点项目赠款（每个40，000 - 50，000美元）或种子赠款 （每项5 000至10 000美元）。此外，我们还为暑期学生项目预留了资金（每个项目5,000美元）。自1995年以来， 我们已经在DRP上投资了350万美元，通过68个试点项目，63个种子项目， 赠款和35个暑期学生项目。这些奖项已导致超过3200万美元的后续孢子 和非SPORE同行评审的资金和127篇出版的手稿。在当前的赠款周期内，我们 资助了51个项目：16个试点项目（每个5万美元），4个种子赠款（每个1万美元）和35个暑期学生项目 （每人5000美元）。Maha Hussain博士和Mark Day博士担任DRP的联合主任。侯赛因博士是一位教授， 内科和泌尿外科，并在前列腺的临床研究专业知识国际公认 癌Hussain博士参加了肿瘤学培训补助金。她作为

Recognizing that developmental research funds are an integral part of the SPORE, we commit $205,000 per year to these endeavors. This represents a significant percent in the budget of the UM Prostate SPORE and reflects the continued commitment of this program to the development of innovative translational research in prostate cancer. The focus of the Developmental Research Program (DRP) is to provide investigators the resources to generate preliminary data for the submission of an R01 grant application or an equivalent proposal Investigators from outside the field of prostate cancer are encouraged to apply through campus-wide announcements as well as through personal interactions with the SPORE investigators. We developed a stepwise proposal solicitation and review process for pilot projects utilizing an NIH-type PHS 398 format that has been streamlined for rapid turnaround of research proposals and which recognizes that these projects may have little preliminary data. Investigators may apply for pilot project grants ($40,000 - $50,000 each) or seed grants ($5,000 - $10,000 each). In addition, we set aside funds for summer student projects ($5,000 each). Since 1995, we have invested $3.5 million in our DRP, funding a total of 83 investigators though 68 pilot projects, 63 seed grants and 35 summer student projects. These awards have led to over $32 million in subsequent SPORE and non-SPORE peer-reviewed funding and 127 published manuscripts. During this current grant cycle, we funded 51 projects: 16 pilot projects ($50K each), 4 seed grants ($10K each) and 35 summer student projects ($5K each). Drs. Maha Hussain and Mark Day serve as co-Directors for the DRP. Dr. Hussain is a Professor of Internal Medicine and Urology and is internationally recognized for her clinical research expertise in prostate cancer. Dr. Hussain participates with the Oncology Training Grant. She serves as the