Developmental Research Program

认识到发展研究基金是孢子不可分割的一部分，我们承诺每个 为这些努力奋斗一年。这在UMCCC前列腺癌的预算中占了相当大的比例 孢子和体现了本计划对创新发展的持续承诺 前列腺癌的转译研究。发展研究计划的重点是提供 调查人员能够生成将成为R01拨款申请的初步数据的数据 或者一个同等的提议。来自前列腺癌领域以外的研究人员被鼓励申请 通过校园范围的公告以及通过与孢子的个人互动 调查人员。我们为试点项目制定了一个循序渐进的建议书征求和审查流程，利用 NIH类型的PHS 398格式已被简化，以快速周转研究提案，并 认识到这些项目可能几乎没有初步数据。调查员可申请试点项目 赠款(每年40,000-50,000美元)或种子赠款(每年5,000-10,000美元)。自1995年以来，我们一直在资助 52个试点项目和61个种子赠款，总投资250万美元。这导致了超过20美元的收入 在随后的赠款和101份手稿中获得了100万美元。马哈·侯赛因博士和马克·戴博士担任联合 发展研究项目主任。侯赛因博士是一名内科教授， 她是一名泌尿科医生，因其在泌尿外科领域的科学临床研究专长而在国内和国际上获得认可。 泌尿生殖肿瘤学领域，特别是前列腺癌和膀胱癌。她是“临床”专家。 为研究发展计划。马克·戴博士是一位泌尿学教授，并发表了 广泛应用于前列腺细胞生物学领域。他是这项研究的“基础科学”导师 发展计划。戴医生是泌尿外科培训助学金的PI，并作为导师参与了 癌症生物学培训助学金。侯赛因博士和戴博士与每个项目调查员会面两次，以审查 进步。项目调查人员还参加每月的孢子会议和年度务虚会。

Recognizing that developmental research funds are an integral part of the SPORE, we commit $175,000 per year to these endeavors. This represents a significant percent in the budget of the UMCCC Prostate SPORE and reflects the continued commitment of this program to the development of innovative translational research in prostate cancer. The focus of the Developmental Research Program is to provide investigators the ability to generate data that would become the preliminary data for an R01 grant application or an equivalent proposal. Investigators from outside the field of prostate cancer are encouraged to apply through campus wide announcements as well as through personal interactions with the SPORE investigators. We developed a stepwise proposal solicitation and review process for pilot projects utilizing a NIH-type PHS 398 format that has been streamlined for rapid turn around of research proposals and which recognizes that these projects may have little preliminary data. Investigators may apply for pilot project grants ($40,000 - $50,000 per year) or seed grants ($5,000 - $10,000 per year). Since 1995 we have funded 52 pilot projects and 61 seed grants with a total investment of $2.5 million. This has resulted in over $20 million in subsequent grants and 101 manuscripts. Dr. Maha Hussain and Dr. Mark Day serve as Co- Directors for the Developmental Research Program. Dr. Hussain is a Professor of Internal Medicine and Urology, and is nationally and internationally recognized for her scientific clinical research expertise in the area of genitourinary-oncology, particularly prostate and bladder cancers. She serves as the "clinical" expert for the Research Development Program. Dr. Mark'Day is a Professor of Urology and has published extensively in the area of prostate cell biology. He serves as the "basic science" mentor of the Research Development Program. Dr. Day is the PI of the Urology Training Grant and participates as a mentor in the Cancer Biology Training Grant. Drs. Hussain and Day meet twice with each project investigator to review progress. Project investigators also take part in the monthly SPORE meetings and annual retreat.