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中文摘要
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描述(由申请人提供):本项目支持将于2014年10月23日至26日在犹他湖城湖城喜来登酒店联合举行的白细胞生物学学会第47届年会。本次国家劳工局和国际环境影响调查研究所联席会议将在2010年举行的国家劳工局/国际环境影响调查研究所非常成功的联席会议的基础上再接再厉。2014年联席会议的中心主题将是先天免疫的发展。该计划经过精心设计,以最大限度地提高两个社会之间的科学互动,以促进合作。我们一直在努力创建一个计划,平衡全体会议,小型研讨会和海报会议与明确定义的网络会议。为了促进对话和互动,并保持与会者在会场,食品和饮料将提供在几个休息。已计划举行具体会议,讨论研究项目的转化方面,包括“靶向免疫治疗疾病”会议等。专业发展讲习班被纳入该方案,其中包括赠款写作讲习班,网络技能会议,以及妇女和多样性讲习班。为了最好地促进这一重要领域的科学交流和初级科学家的培训,该提案要求NIH支持2014年SLB年度科学会议,题为“先天免疫的发展”,以允许参与者通过旅行奖励和分担费用获得更多的机会。 具体目标1。提供一个探讨先天免疫如何发展的新概念的学术论坛。具体会议将讨论(1)适当使用动物模型来了解人类疾病,(2)生物工程和微流体,(3)骨髓细胞前体,(4)免疫发育,(5)免疫个体发育和(6)疫苗开发。这些主题与我们对严重疾病的理解至关重要,包括传染病,癌症和心血管疾病以及由自身免疫性疾病引起的无菌炎症。该计划将邀请该领域的知名领导人和后起之秀进行演讲,以及从全球实验室提交的摘要中选出的初级研究人员/学员进行口头和/或海报演示。会议将针对来自学术、政府、临床和工业实验室的约350-450名与会者。 具体目标2。通过海报和口头会议的密切互动,为年轻的研究人员和学员提供与知名科学家密切互动的机会。将举办一个专门的职业发展讲习班以及一个关于赠款编写和出版的培训班,以促进有抱负的学生和初级调查员的培训和发展。将根据科学成绩向选定的与会者发放旅费。本次会议的参与者人数较少,海报会议有充足的时间,为初级研究人员创造了一个学院式的学习环境,以便与先天免疫发育领域的领先科学家进行严格的讨论。具体目标3。通过促进妇女、少数民族和残疾科学家的参与,促进白细胞生物学和先天免疫领域的多样性。将举办一个专门论坛,重点讨论妇女和少数群体科学家面临的障碍,并将组织网络和职业发展讲习班,以解决职业发展的障碍和机会。
英文摘要
DESCRIPTION (provided by applicant): This project supports the 47th Annual Meeting of the Society for Leukocyte Biology, jointly with the International Endotoxin and Innate Immunity Society (IEIIS), to be held at the Salt Lake City Sheraton, Salt Lake City, Utah during October 23-26, 2014. This joint meeting of SLB and IEIIS will build upon the highly successful joint SLB/IEIIS meeting held in 2010. The central theme of the 2014 joint meeting will be the development of innate immunity. The program has been carefully designed to maximize scientific interactions between the two societies to foster collaborations. We have worked diligently to create a program that balances plenary sessions, mini-symposia and poster sessions with clearly defined networking sessions. To facilitate dialog and interaction, and keep attendees at the meeting venue, food and beverages will be provided at several of the breaks. Specific sessions have been planned to discuss the translational aspects of research projects, including a session "Targeting Immunity to Treat Disease" among others. Professional development workshops are incorporated into the program which include a grant writing workshop, a session on networking skills, and a Women and Diversity workshop. To best facilitate scientific exchange and training of junior scientists in this important area, this propoal requests NIH support for the 2014 SLB annual scientific conference entitled "Development of Innate Immunity" to allow greater access for participants via travel awards and shared costs. Specific Aim 1. To provide a collegial forum exploring new concepts on how innate immunity develops. Specific sessions will address (1) Appropriate use of animal models to understand human disease, (2) Bioengineering and microfluidics, (3) Myeloid cell precursors, (4) immune phylogeny, (5) immune ontogeny and (6) vaccine development. These topics bear critical relevance to our understanding of severe diseases including infectious diseases, cancer, and cardiovascular disease as well as sterile inflammation resulting from autoimmune diseases. The program will feature invited presentations from established leaders and rising stars in the field, as well as oral and/or poster presentations by junior investigators/ trainees selected from among the abstracts submitted by laboratories worldwide. The meeting will target approximately 350-450 participants from academic, governmental, clinical and industrial laboratories. Specific Aim 2. To provide an opportunity for young investigators and student trainees to interact closely with established scientists, through close interaction in both poster and oral sessions. A dedicated career development workshop as well as a training session on grant writing and publication will be held to foster the training and development of aspiring students and junior investigators. Travel awards will be administered to selected participants based on scientific merit. The smaller number of participants and ample time for the poster sessions at this meeting creates a collegial learning environment for junior investigators to engage in rigorous discussion with the leading scientists in the area of innate immunity development. Specific Aim 3. To promote diversity in the field of leukocyte biology and innate immunity by fostering the participation of women, minority, and disabled scientists. A specific forum focusing on obstacles facing women and minority scientists will be held and networking and professional career development workshops will be organized to address obstacles and opportunities for career development.
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Modulation of innate immune exhaustion during sepsis
Novel mechanisms for the generation of resolving monocytes
Altered innate leukocyte programming dynamics in sepsis
Altered innate leukocyte programming dynamics in sepsis
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