Innate Cell Plasticity Conference-Society of Leukocyte Biology

描述(申请人提供)：白细胞生物学学会(SLB)是领先的科学协会，专注于促进白细胞及其在急性和慢性疾病病理生理学中的作用的研究，从感染、心血管炎症、癌症到神经疾病。从历史上看，SLB年会吸引了来自学术界、工业界和医疗保健组织的多学科与会者。该计划包括受邀的全体会议、主旨和专题讨论会演讲者，以及从提交的摘要中挑选的演讲者，以及海报会议和特别节目。商业参展商，包括研究和临床试剂的制造商和分销商以及科学出版商也参加了会议。以证明SLB在科学上的卓越和 SLB年会、以往SLB年会的与会者和现任SLB成员包括诺贝尔奖获得者、科学院成员以及基础和转化白细胞生物学方面的世界领袖。2013年会议将延续这一卓越传统，将所有级别的科学研究人员聚集在一个环境中，以便最大限度地促进思想交流的互动，促进研究合作，继续以加快基础研究和翻译研究的进展为目标。2013年年会的中心主题突出了关于先天白细胞表型/功能可塑性及其在急性和慢性炎症条件下的关键调节作用的更具先见之明的主题。为了更好地促进这一重要领域的科学交流和初级科学家的培训，本提案请求国立卫生研究院为2013年SLB年度科学会议提供支持，题为“天生细胞可塑性的调节器”，以允许与会者通过旅行奖励和分担费用获得更多机会。具体目标1.为介绍和讨论天然细胞可塑性的新概念、其病理生理学意义和翻译应用提供一个有凝聚力、合议性和及时性的论坛。这些将包括(1)对新的天然白细胞亚群的最新了解，(2)天然细胞记忆、可塑性和转换/重编程的紧迫范式，(3)天然细胞与内皮/上皮细胞之间的集成串扰，(4)定义天然细胞微生物相互作用的新方法，以及(5)天然细胞可塑性与感染、癌症、心血管疾病和衰老等疾病的发病机制的翻译相关性。该方案将包括该领域领导人的应邀演讲，以及从世界各地实验室提交的摘要中挑选出来的初级调查人员/受训人员的口头和/或海报介绍。这次会议的目标是来自学术、政府、临床和工业实验室的大约350-400名与会者。具体目标2.为青年研究人员和受训人员提供机会，与他们所在领域的顶级、知名研究人员密切互动，并在海报和讲台/口头会议上介绍他们的研究成果。将举办专门的职业发展讲习班以及关于赠款编写和出版的培训课程，以促进有抱负的学生和初级调查人员的培训和发展。旅行奖励将根据科学价值颁发给选定的参与者。本次会议参与人数较少，海报会议时间充裕，为初级调查人员与白细胞生物学领域的领先科学家进行严谨讨论创造了一个大学学习环境。具体目标3.促进妇女、少数民族和残疾科学家参与重要的白细胞生物学生物医学领域。将举行一次专门论坛，重点讨论妇女和少数民族科学家面临的障碍。将举办联网和职业发展讲习班，以解决职业发展的障碍和机会。

DESCRIPTION (provided by applicant): The Society for Leukocyte Biology (SLB) is the leading scientific society with a focus on facilitating research on leukocytes and their roles in te patho-physiology of both acute and chronic diseases ranging from infection, cardiovascular inflammation, cancer, to neurological diseases. Historically, the SLB annual meetings draw multi-disciplinary attendees from academia, industry, and health care organizations. The program consists of invited plenary, keynote and symposium speakers, as well as speakers selected from submitted abstracts, plus poster sessions and special programs. Commercial exhibitors including manufacturers and distributors of research and clinical reagents and scientific publishers also attend the conference. To attest to the scientific excellence of SLB and SLB annual meetings, past attendees of SLB annual meetings and current SLB members include Nobel Laureates, Academy members, and world leaders in basic and translational leukocyte biology. The 2013 meeting will continue this tradition of excellence by bringing together scientific researchers of all levels in an environment geared to maximize interactions for the exchange of ideas, foster research collaborations, with the continued goal of accelerating progress in basic and translational research. The central theme of the 2013 annual meeting highlights the more prescient topics concerning innate leukocyte phenotypic/functional plasticity and their key modulatory roles in both acute and chronic inflammatory conditions. To best facilitate scientific exchange and training of junior scientists in this important area, this propoal requests NIH support for the 2013 SLB annual scientific conference entitled "Regulators of Innate Cell Plasticity" to allow greater access for participants via travel awards and shared costs. Specific Aim 1. To provide a cohesive, collegial and timely forum for presentation and discussion of emerging concepts in the regulation of innate cell plasticity, it's patho-physiologicl significance and translational application. These will include (1) most updated understandings of novel innate leukocyte subsets, (2) pressing paradigms of innate cell memory, plasticity and conversion/reprogramming, (3) integrated cross-talk among innate cells with endothelial/epithelial cells, (4) novel approaches in defining innate cell microbial interactions, and (5) the translational relevance of innate cell plasticity to the pathogenesis of conditions tha include infection, cancer, cardiovascular disease and aging. The program will feature invited presentations from leaders in the field, as well as oral and/or poster presentations by junior investigators/ trainees selected from among the abstracts submitted by laboratories worldwide. The meeting will target approximately 350-400 participants from academic, governmental, clinical and industrial laboratories. Specific Aim 2. To provide an opportunity for young investigators and trainees to interact closely with top echelon, well-established researchers in their fields, and to present their research findings in both poster and podium/oral sessions. A dedicated career development workshop as well as training session on grant writing and publication will be held to foster the training and development of aspiring students and junior investigators. Travel awards will be administered to selected participants based on scientific merits. The smaller number of participants and ample time for the poster sessions at this meeting creates a collegial learning environment for junior investigators to engage in rigorous discussion with the leading scientists in the area of leukocyte biology. Specific Aim 3. To foster the participation of women, minority, and disabled scientists in the important biomedical field of leukocyte biology. A specific forum focusing on obstacles facing women and minority scientists will be held. Networking and professional career development workshops will be organized to address obstacles and opportunities for career development.