UAB Center for Clinical and Translational Science (CCTS)

联系PD/PI：金伯利，Robert P 临床和转化科学中心(CCTS)的愿景是减少 疾病在南方腹地不成比例地出现，因为我们加快了发现以改善人类 健康。我们已经建立了一个强大的合作伙伴网络-横跨阿拉巴马州、密西西比州和路易斯安那州- 确保我们的研究和培训努力服务于本地区的特殊人群，同时最大限度地 翻译研究中的协同增效作用(目标1)。我们推动一个多元化、多元化、 代表所有职业阶段的多学科研究团队，通过支持广泛的NRSA产品组合 培训、受指导的职业发展、具体内容的教育计划和体验式学习 机遇(目标2)。这些倡议加深了对临床和转化科学的科学理解， 建立核心能力并在良好的临床实践、研究设计、 生物伦理学、临床试验和团队科学的开展。CCTS支持符合伦理、科学严谨的临床 通过集中努力在整个CCTS合作伙伴网络(AIM 3)上进行试验和试点研究，以提供 基因组学、信息学、生物统计学和流行病学方面的资源、专门服务和咨询； 临床研究、先进成像和药物发现。CCTS促进了最佳做法的应用， 包括由CTSA联盟建立的工具，并将促进能够快速和高效地 执行多点临床试验，利用电子健康记录告知可行性和 接触研究人群的机会。重要的是，为了与我们缩小区域健康差距的目标保持一致，我们 认识到让我们的社区参与规划和进行研究的重要性(目标4)。 通过我们的社区参与部门-一个伟大的社区-我们正在扩大方案外展 将成功的以社区为基础的参与性研究方法推广到区域范围。最后，我们 了解评估CCTS合作伙伴网络活动的重要性，以确保我们 完成我们的目标(目标5)。教学计划、社区参与和研究过程 由一组量身定做的通用指标进行评估，以指导战略并概述进展情况 实现明确的目标。通过实现这些目标，CCTS合作伙伴网络将加快临床和 在南方腹地进行翻译研究，推动改善面临的重大健康差距 被我们的人口。此外，CCTS中心及其合作伙伴网络将处于有利地位，可以与其他 HUBS和CTSA联盟在传播临床和转化性研究和 训练。 项目摘要/摘要页248 联系PD/PI：金伯利，Robert P

Contact PD/PI: Kimberly, Robert P The vision of the Center for Clinical and Translational Science (CCTS) Hub is to reduce health disparities in diseases disproportionately represented within the Deep South as we accelerate discovery to improve human health. We have established a robust Partner Network – spanning Alabama, Mississippi and Louisiana – to ensure that our research and training efforts serve the special populations in our region while maximizing collaborative synergies in translational research (Aim 1). We promote the continued development of a diverse, multidisciplinary research workforce representing all career stages, by supporting a broad portfolio of NRSA training, mentored career development, content specific educational programs and experiential learning opportunities (Aim 2). These initiatives deepen scientific understanding of clinical and translational science, establish core competencies and advance the knowledge base in good clinical practice, study design, bioethics, conduct of clinical trials and team science. The CCTS supports ethical, scientifically rigorous clinical trials and pilot research across the CCTS Partner Network (Aim 3) through focused efforts to provide resources, specialized services and consultation in genomics, informatics, biostatistics and epidemiology, clinical research, advanced imaging and drug discovery. The CCTS fosters the application of best practices, including those established by the CTSA Consortium, and will promote tools that enable the rapid and efficient execution of multi-site clinical trials, taking advantage of the electronic health record to inform feasibility and access to study populations. Importantly, in keeping with our goal of reducing regional health disparities, we recognize the importance of engaging our communities in the planning and conduct of research (Aim 4). Through our community engagement arm – One Great Community – we are expanding programmatic outreach by taking successful community-based participatory research approaches to a regional scale. Finally, we understand the importance of evaluating the activities of the CCTS Partner Network to ensure that we are accomplishing our goals (Aim 5). Didactic programs, community engagement and research processes are evaluated by a panel of tailored and common metrics to guide strategies and outline progress towards achieving defined goals. By achieving these aims, the CCTS Partner Network will accelerate clinical and translational research in the Deep South and advance the amelioration the significant health disparities faced by our populations. Further, the CCTS Hub and its Partner Network will be well-positioned to work with other hubs and the CTSA Consortium in the dissemination of best practices in clinical and translational research and training. Project Summary/Abstract Page 248 Contact PD/PI: Kimberly, Robert P