Pittsburgh-Stellenbosch University AIDS-comorbidities Training Research Program (Pitt-SU AICoTRP)

 描述（由申请人提供）：非洲的大多数大学都受到缺乏资源和专业知识的限制，无法开展，促进和建设研究能力，以应对上述健康挑战。极少数合格的学术专业人员有教学和临床义务，很少或根本没有保护时间进行研究。此外，由于缺乏完善的学术职业道路，以及当地导师数量有限，特别是在艾滋病毒合并症的新兴领域，前往海外接受进一步培训的有前途的研究人员很少回国。我们提出的培训计划的总体目标是建立下一代南非艾滋病毒合并症研究人员的临界质量，他们可以独立进行，并促进当地相关研究的使用，成为独立和成功的调查人员。具体目标是装备初级教师和博士后学生：1）获得研究方法，研究道德和负责任的研究行为的知识：2）进行本地驱动的研究，解决艾滋病毒相关的血管疾病，神经精神病学和慢性肾脏疾病的本地相关研究问题; 3）获得科学演讲和写作，演讲，指导和研究管理方面的技能;（4）与公众建立密切联系，我们的目标是为政策制定者和利益攸关方提供一个可持续发展的平台，以便将研究成果转化为临床实践和公共卫生政策。我们将通过在南非开普敦的斯泰伦博斯大学开展协调良好的综合培训方案来实现这些目标，以提高艾滋病毒合并症的研究能力，包括在伙伴机构（开普敦大学、约翰霍普金斯大学、匹兹堡大学和哈佛公共卫生学院）开展共同辅导和短期培训。用于建立和提高研究能力的战略将包括：教学课程、指导高质量研究、体验式学习、试点研究赠款、讲习班/会议、研讨会、艾滋病毒合并症期刊俱乐部和网站资源。将使用面对面和远程学习技术。执行委员会（EC）在与培训咨询委员会（TAC）协商后，将批准招募、研究、监测和评估至少6名高质量的受训人员，他们每人将获得一笔发展性试点研究补助金和25%至50%的受保护研究时间，为期5年。每个受训者都将有一个个性化的职业发展计划，该计划将在整个任期内和计划完成后进行监测和跟踪。学员将与他们的导师一起制定此计划。

 DESCRIPTION (provided by applicant): Most universities in Africa are limited by the lack of resources and expertise for conducting, promoting and building capacity in research to address the above health challenges. The very few available qualified academic professionals have teaching and clinical obligations with little or no protected time for research. In addition, promising researchers who travel overseas for further training rarely return home due to the lack of well-established academic career paths, and the limited number of available local mentors, especially in the emerging field of HIV-comorbidities.The overall objective of our proposed training program is to build a critical mass of the next generation of top South African HIV co-morbidities researchers who can independently conduct, and promote the use of, locally relevant research, become independent and successful investigators. The Specific Aims are to equip junior faculty and post-doctoral students: 1) to gain knowledge in research methodology, research ethics and responsible conduct of research: 2) to conduct locally driven research that addresses locally relevant research questions in HIV-associated Cardio-Vascular Disease, Neuropsychiatry, and Chronic Kidney Disease; 3) to gain skills in scientific presentations and writing, grantsmanship, mentoring and research management; 4) to develop close engagement with the public, policymakers and stakeholders in order to translate research findings into clinical practice and public health policies. We will achieve these aims through a well-coordinated and comprehensive training program at Stellenbosch University, Cape Town, South Africa, to enhance research capacity in HIV comorbidities, including co-mentoring and short-term training in partnering institutions (University of Cape Town, Johns Hopkins University, Pittsburgh University and Harvard School of Public Health. The strategies utilized to build and enhance research capacity will include: didactic coursework, mentored high-quality research, experiential learning, pilot research grants, workshops/conferences, seminars, HIV comorbidities journal clubs, and website resources. Both face-to-face and distance learning techniques will be used. An Executive Committee (EC), after consultation with a Training Advisory Committee (TAC), will approve the recruitment, research, monitoring and evaluation of at least 6 high quality trainees, who will each be provided a developmental pilot research grant and 25% to 50% of protected research time for 5 years. Each trainee will have an individualized career development plan that will be monitored and tracked throughout their tenure and after completion of the program. Trainees will develop this plan in conjunction with their mentor(s).