11th Structural Birth Defects Meeting

 描述(由申请人提供)：在过去的15年里，尤尼斯·肯尼迪·施莱弗国家儿童健康与人类发展研究所组织了十次结构性出生缺陷会议，目的是将由NICHD出生缺陷倡议资助的调查人员聚集在一起。这些会议的首要目标是为交流研究成果营造一个合作的环境，以加强将功能基因组研究的基本知识和见解转化为开发新的、创新的和有效的人类结构性出生缺陷诊断、治疗和预防策略。资助的研究人员跨越多个学科，包括发育生物学家、细胞生物学家、生物物理学家、临床医生、基因学家、遗传学家、流行病学家以及生物统计学家和生物信息学家。在任何一次给定的会议上，都有50-60名调查人员以及NIH的相关工作人员参加。在2014年12月举行的第10次结构性出生缺陷会议上，决定将今后会议的规划工作从NICHD工作人员过渡到结构性出生缺陷研究界，从而为研究界的其他人，特别是受训者的出席铺平了道路。本申请旨在为第11届结构性出生缺陷会议寻求资金，该会议将于2017年4月3-5日在马里兰州贝塞斯达举行，由发育生物学学会(SDB)赞助，地点为美国实验生物学学会联合会(FASEB)会议中心。其目的是将会议规模扩大一倍以上，同时保持发言和讨论的互动性和多学科性质。没有同时进行的会议，预计所有参与者都将参加所有的演讲。会议的形式主要是对假设驱动的结论作简短的陈述，分成几个专题领域，然后进行讨论。按照传统，邀请一位主旨演讲者来自一个不一定是出生缺陷研究的主流但与该领域高度相关的领域，从而促进新思想的讨论和交流。邀请第二位发言者介绍一个专题，随后圆桌会议小组和所有与会者将更正式地讨论该专题。将首次举行招贴会，以便利受训人员尽可能多地参与。这些活动将在两天延长的午餐休息时间举行，以便所有人都能充分参与。非正式的晚间活动将吸引资深科学家和受训人员参与，以鼓励指导和建立联系。

 DESCRIPTION (provided by applicant): For the past 15 years, the Eunice Kennedy Shriver National Institute of Child Health & Human Development has organized ten Structural Birth Defects Meetings with the goal of bringing together investigators funded through the NICHD Birth Defects Initiative. The overriding goal of these meetings has been to foster a collaborative environment for the exchange of research findings to enhance the translation of basic knowledge and insights from functional genomic studies into the development of new, innovative, and efficacious strategies for the molecular diagnosis, treatment, and prevention of human structural birth defects. Funded investigators spanned multiple disciplines and included developmental biologists, cell biologists, biophysicists, clinicians, genomicists, geneticists, epidemiologists, and biostatisticians and bioinformaticians. At any given meeting, 50-60 investigators attended as well as relevant NIH staff. At the 10th Structural Birth Defects Meeting in December 2014, a decision was made to transition the planning of future meetings from NICHD staff to the structural birth defects research community opening the way for attendance by others from the research community and, in particular, trainees. This application seeks funding for the 11th Structural Birth Defects Meeting to be held April 3-5, 2017 in Bethesda, MD at the Federation of American Societies for Experimental Biology (FASEB) Conference Center under the sponsorship of the Society for Developmental Biology (SDB). The intent is to more than double the size of the meeting while maintaining the interactive, multidisciplinary nature of the presentations and discussions. There are no concurrently running sessions and all participants are expected to attend all the presentations. The format of the meeting consists predominately of short presentations of hypothesis driven findings grouped into several topic areas followed by discussion. As has become the tradition, a keynote speaker is invited from an area not necessarily mainstream to birth defects research but of high relevance to the field thus stimulating discussion and exchange of new ideas. A second speaker is invited to introduce a topic which will then be discussed more formally by a roundtable panel as well as all participants. For the first time poster sessions will be held to facilitate participation of as man trainees as possible. These will be held during extended lunch breaks on two days allowing for adequate participation by all. Informal evening activities will engage senior scientists and trainees to encourage mentoring and networking.