Pneumococcal vaccines and long-term protection

肺炎球菌病是全世界5岁以下儿童的最大杀手之一，主要发生在发展中国家。肺炎球菌结合疫苗在减少肺炎球菌疾病方面非常有效，但保护的持续时间和所涉及的免疫因素尚不清楚，特别是在使用剂量少于建议剂量的情况下。我的研究旨在研究肺炎球菌疫苗接种后提供长期保护的关键免疫因素。

Pneumococcal disease is one of the biggest killers of children under 5 years of age worldwide, mostly in developing countries. Pneumococcal conjugate vaccines are highly effective at reducing pneumococcal disease however the duration of protection and the immune factors involved is unknown, particularly when fewer than the recommended number of doses are used. My fellowship aims to examine the key immune factors that provide long-term protection following pneumococcal vaccination.