Characterizing the regulators of mitochondrial biogenesis in Arabidopsis thaliana

这个项目的总体目标是识别和描述控制植物线粒体质量和数量的潜在调控因素。该项目将利用一种将线粒体进口机制和呼吸链联系起来的监管机制。利用正向和反向遗传方法，蛋白质输入易位酶的丰度将被改变，线粒体生物发生的变化将被调查。这将确定调控因素，这些因素可以被操纵并用于改变线粒体的数量和活性。

The overall aim of this project is to identify and characterise the underlying regulatory factors that control mitochondrial mass and number in plants. The project will exploit a regulatory mechanism that links the mitochondrial import machinery and the respiratory chain. Utilising both forward and reverse genetic approaches, the abundances of protein import translocases will be altered and the changes to mitochondrial biogenesis will be investigated. This will identify regulatory factors, which can be manipulated and used to alter mitochondrial number and activity.