Predicting perioperative cognitive disorders in the elderly based on cardiovascular risk, AD risk and new biomarkers

麻醉和手术在老年人中很常见，众所周知会导致记忆和思维问题。目前尚不清楚为什么会发生这种情况。我计划研究手术前后的困惑、记忆和思维问题，并确定血液或脑脊液测试或修改心血管疾病是否可以预测这种情况的发生。这项工作将有助于及早识别麻醉和手术后有认知问题风险的人，并找到预防这种情况发生的方法。

Anaesthesia and surgery are common in the elderly and are known to lead to memory and thinking problems. Why this happens is unclear. I plan to study confusion, memory and thinking problems before and after surgery and to determine if blood or cerebrospinal fluid tests or modifying cardiovascular disease can predict this happening. This work will lead to early identification of people who are at risk of cognitive problems following anaesthesia and surgery, and ways to prevent this happening.