Predictive Models to Design and Develop New Antibiotics Derived from the Community for Open Antimicrobial Drug Discovery

随着耐多药细菌感染的增加，以及正在开发的抗生素有限，需要新的策略来产生新的抗生素。该项目将应用人工智能方法来研究一个独特的数据集，该数据集是在全球300多个学术团体的帮助下，在5年多的时间里生成的。它将产生预测模型，然后应用于设计新的抗生素，这些抗生素将被合成并测试其抗菌活性。

With the rise of infections from multidrug-resistant bacteria, and limited antibiotics in the development pipeline, new strategies are required to generate novel antibiotics. This project will apply artificial intelligence methods to study a unique dataset generated over five years with the help of over 300 academic groups around the world. It will produce predictive models that will then be applied to design new antibiotics, which will be synthesized and tested for antimicrobial activity.