Probiotic Prawn Oral Immunotherapy (ProPIT) for Treatment of Prawn Allergy

需要一种“治愈性”食物过敏治疗来预防死亡和改善护理。我们最近发现益生菌花生口服免疫疗法（PPOIT）治疗花生过敏非常有效。接受PPOIT治疗的儿童中有82%获得了耐受性，而安慰剂组只有4%。现在，我们将测试益生菌-食物OIT联合治疗对虾过敏的方法。如果成功，我们将确定对虾过敏的第一种治疗方法，并为其他食物过敏提供平台治疗。

A ‘curative’ food allergy treatment is needed to prevent deaths and improve care. We recently showed that probiotic peanut oral immunotherapy (PPOIT) was highly effective for treating peanut allergy. 82% of PPOIT treated children gained tolerance compared to 4% of the placebo group. We will now test the combined probiotic-food OIT approach for treating prawn allergy. If successful, we will have identified the first treatment for prawn allergy and a platform treatment for other food allergies.