Rationally Designed Targeted Core Shell Nano-Construct for Improved Anticancer Effects and Enhanced Bone Fracture Healing in Breast Cancers Metastasised to Bone

该项目的主要目的是开发和评估一种单一的治疗系统，包括化疗以及骨折愈合剂，这将克服骨骼骨转移乳腺癌的传统治疗的缺点。这种治疗系统将特异性地在肿瘤部位积聚并释放化疗剂，从而实现抗癌作用，随后缓慢释放骨折愈合剂，导致骨折愈合。

The main objective of the project is to develop and evaluate a single therapeutic system comprising chemotherapeutic as well as bone fracture healing agent, which will overcome the drawbacks of the conventional treatment for skeletal bone metastasised breast cancers. This therapeutic system will specifically accumulates in the tumour sites and release the chemotherapeutic enabling anticancer effects, followed by the slow release of bone fracture healing agent results in healing of fractures.