Rationally Designed Targeted Core Shell Nano-Construct for Improved Anticancer Effects and Enhanced Bone Fracture Healing in Breast Cancers Metastasised to Bone

该项目的主要目标是开发和评估一种包括化疗和骨折愈合剂的单一治疗系统，这将克服传统治疗骨骼转移性乳腺癌的缺点。这种治疗系统会特异性地在肿瘤部位积累，释放出具有抗癌作用的化疗物质，随后缓慢释放骨折愈合剂，导致骨折愈合。

The main objective of the project is to develop and evaluate a single therapeutic system comprising chemotherapeutic as well as bone fracture healing agent, which will overcome the drawbacks of the conventional treatment for skeletal bone metastasised breast cancers. This therapeutic system will specifically accumulates in the tumour sites and release the chemotherapeutic enabling anticancer effects, followed by the slow release of bone fracture healing agent results in healing of fractures.