An investigation of the involvement of clotting factors in abdominal aortic aneurysm (AAA) progression within a mouse model
An investigation of the involvement of clotting factors in abdominal aortic aneurysm (AAA) progression within a mouse model
小鼠模型中凝血因子参与腹主动脉瘤 (AAA) 进展的研究
批准号：
nhmrc : 1016349
负责人：
Dr Sai Wang Seto
金额：
$12.63万
依托单位：
依托单位国家：
澳大利亚
项目类别：
Early Career Fellowships
财政年份：
2011
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2011-01-01 至 2012-12-31
中文摘要
翻译
大约100,000名澳大利亚人出现早期腹主动脉衰弱，目前还没有公认的治疗方法。迫切需要开发限制衰弱过程进展的药物疗法。在这项研究中，我们将探讨凝血级联在动脉变弱中的作用。这项研究计划是为了确定新的策略，这些策略可以被开发为治疗患者动脉变弱的方法。
英文摘要
Early stage weakening of the main abdominal artery is present in ~100,000 Australians and currently has no accepted therapy. Development of drug therapies which limit progression of the weakening process is urgently needed. In this study involvement of the clotting cascade in artery weakening will be investigated. The study have been planned in order to identify new strategies which can be developed as treatments for artery weakening in patients.
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