The Augmented versus Routine approach to Giving Energy Trial (TARGET)

危重病人经常吃不饱饭。研究人员开发了一种简单的策略，可以可靠地实现100%的卡路里目标。策略是用能量密集的养分取代标准养分，并以相同的速度提供。这项研究的目的是确定增加卡路里供应对危重疾病后长期生存和功能的影响。将进行一项有4000名患者、多中心、双盲、随机、临床试验。

Critically ill patients are routinely underfed. The investigators have developed a simple strategy that reliably delivers 100% of caloric goals. The strategy is to substitute standard nutrient with energy dense nutrient and deliver it at the same rate. The aim of this study is to determine the effect of increased calorie delivery on long-term survival and function following critical illness. A 4000-patient, multicentre, double-blind, randomised, clinical trial will be performed.